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Terms Of Use

CYCLIZINE

Brand Name(s) : Valoid
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

CYCLIZINE WARNINGS

Cyclizine should be used with caution in:

It should not be used in:

  • People with allergy to cyclizine, or any of the ingredients in the medicine
  • People with porphyria (hereditary blood disorder)
  • People with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption
  • Children, under 6 years of age (for tablets)

Also see list of precautions and interactions

STORAGE

Store below 25°C. Protect from light by keeping the medication in its original packaging.

CYCLIZINE USES

What is it used for?

  • Cyclizine is used to prevent nausea and vomiting.
  • It is known as an antihistamine with anticholinergic properties, sometimes known as an anti-emetic.
  • It is used to prevent and treat the symptoms of nausea and vomiting due to a variety of causes. Cyclizine is also used to prevent vertigo.
  • In general this drug is used to prevent and relieve nausea and vomiting due to travel sickness, middle ear disorders, radiotherapy and before and after operations.
  • Benefits of being on this drug can include effective prevention and relief of feeling and being sick.

Listed below are the typical uses of cyclizine.
Prevention and relief of:

  • Travel sickness
  • Nausea and vomiting caused by strong pain killers and general anaesthetics after an operation (given after an operation)
  • Vomiting due to radiotherapy, especially for breast cancer (radiation sickness)
  • Vomiting and vertigo, associated with Meniere's disease (a disorder of the middle ear affecting balance)
  • Prevention of:Nausea, vomiting and inhalation of stomach contents during an operation caused by general anaesthetics (given before the operation, for injection only)

On occasion your doctor may prescribe this medicine to treat a condition not on the above list.

HOW TO USE/TAKE

This medication can be taken in tablet form or as an injection.

How often do I take it?

  • Tablets: Take this medication by mouth usually three times daily, with or without food.
  • Injection: This medication will be given to you by a doctor or nurse by either the intravenous (into a vein) or intramuscular (into a muscle) route, without food. It can be given up to three times daily.
  • Use this medication for the duration of the prescription in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • Tablets (cyclizine hydrochloride): It may take up to 1 to 2 hours before the full benefit of this drug takes effect. The effect lasts for 4 to 6 hours.
  • Injection (cyclizine lactate): The medication will start to have an effect within 20 minutes (depending on route of injection), but it may take up to 2 hours before the full benefit of this drug takes effect. The effect lasts for about 4 hours.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • This medication may cause drowsiness or dizziness. If you are affected you should avoid driving or operating machinery. Consult your doctor or pharmacist for more details. Consult your doctor or pharmacist for more details.

When can I stop?

  • Always complete the full course as prescribed by your doctor.

CYCLIZINE SIDE EFFECTS

  • Allergic skin reactions including red, itchy rash (known as urticaria, hives or nettle rash)
  • Drowsiness
  • Headache
  • Dry mouth, nose and throat
  • Blurred vision
  • Increased heart rate
  • Problems urinating
  • Constipation
  • Restlessness
  • Nervousness
  • Problems sleeping
  • Hallucinations (both visual and auditory)
  • Abnormal movements, such as tremor, twitching and spasms
  • Disorientation
  • Dizziness
  • Decreased consciousness
  • Speech difficulties
  • High blood pressure
  • Tingling feeling in hands and/or feet
  • Yellowing of eyes or skin
  • Inflammation of the liver
  • Breathing difficulties
  • For injection only: reactions at site of injection such as vein tracking, reddening of the skin, pain and blood clots. The injection may result in a lowering of blood pressure (hypotensive effect).

If any of these persist or you consider them severe then inform doctor or pharmacist.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

CYCLIZINE PRECAUTIONS

Before taking cyclizine, tell your doctor or pharmacist if you are allergic to it; or to other antihistamines; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • Allergy to cyclizine, or any of its ingredients
  • Porphyria (hereditary blood disorder)
  • Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following:

  • Glaucoma
  • Obstructive disease of the stomach
  • Liver disease
  • Epilepsy (fits)
  • Prostatic hypertrophy (enlargement of prostate gland)
  • Severe heart failure
  • Decreased kidney function

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • It is recommended not to drink alcohol while taking this medication, due to potentially dangerous effects.

The elderly: cyclizine may be used in the elderly with caution.

Pregnancy and breast-feeding - please ensure you read the detailed information below

PREGNANCY

The safety of cyclizine has not been established during pregnancy, and is therefore not recommended. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

It is not known whether cyclizine passes into breast milk. The manufacturer therefore states that it should not be taken if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

CYCLIZINE INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur: none known

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Alcohol or other medicines which have an effect on breathing rate and sleepiness including sleeping pills and some drugs used to treat mental health problems.
    -Tricyclic antidepressants (for depression, such as amitriptyline, imipramine)
    -Tranquilisers, sedatives, hypnotics, anxiolytics (for sleeping troubles and anxiety, such as zopiclone, diazepam, nitrazepam)
    -Antipsychotics (for psychosis, such as haloperidol, chlorpromazine, clozapine)
  • Pethidine
  • Medicines which have an anticholinergic effect such as some used to treat Parkinson's disease or urinary problems

This information does not contain all possible interactions. Therefore, before using cyclizine, tell your doctor or pharmacist of all the products you use.

CYCLIZINE OVERDOSE

Symptoms of overdose may include dry mouth, nose and throat, blurred vision, increased heart rate and problems urinating. Other symptoms that may occur include drowsiness, dizziness, lack of coordination, weakness, over excitability, disorientation, lack of judgement, hallucinations, abnormal movements, fever and breathing difficulties.

Overdoses in children are more likely to result in convulsions (fits).

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of cyclizine or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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