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DILTIAZEM

Brand Name(s) : Adizem sr, adizem xl, Angitil sr, Angitil xl, Bi-carzem sr, BI-carzem xl, Calcicard cr, Dilzem sr, Dilzem xl, Slozem, Tildiem, Tildiem la200, Tildiem la300, Tildiem retard, Viazem xl, Zemtard xl
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

DILTIAZEM WARNINGS

Diltiazem should be used with caution in:

It should not be used in:

  • Allergic (hypersensitive) to diltiazem
  • Pregnancy
  • Breastfeeding
  • Taking dantrolene, a medicine used for severe muscle spasms or severe fever
  • Acute porphyria ( an inherited disorder of the red blood pigment haemoglobin)
  • A very slow heartbeat - less than 50 beats per minute
  • Heart failure and problems with blood flow to your lungs.
  • Any other serious problems with your heart, including an uneven heartbeat (unless you have a pacemaker)

Also see list of precautions and interactions

STORAGE

Store below 25°C in the original packaging.

DILTIAZEM USES

What is it used for?

  • Diltiazem is used to treat high blood pressure and chest pain caused by angina.
  • It is a calcium channel antagonist, sometimes known as calcium channel blocker.
  • It is used to expand the blood vessels, which lowers your blood pressure and makes it easier for your heart to pump blood around your body, which reduces the chest pain caused by angina.
  • In general this drug is used treat high blood pressure, to reduce chest pain caused by angina, and to prevent you having such chest pain in the future.
  • Benefits of being on this drug can include lowering your blood pressure, reduced chest pain, and fewer episodes of angina.

Listed below are the typical uses of diltiazem.

  • High blood pressure
  • Chest pain caused by angina
  • Irregular heart beat (arrhythmia)

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • A type of angina known as Prinzmetal's angina, which you experience when resting rather than on exertion and therefore it often occurs at night.

HOW TO USE/TAKE

How often do I take it?

  • Take this medication orally usually up to three times a day with water, before or during a meal.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take up to 2 weeks before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • You may feel dizzy while taking this medicine. If this happens, do not drive or use any tools or machines. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

DILTIAZEM SIDE EFFECTS

  • Upset stomach
  • Feeling sick
  • Dizziness
  • Headache
  • Tiredness
  • Swelling of the legs
  • Flushing (redness of the face).
  • Low blood pressure (feeling dizzy, light-headed or faint when you stand or sit up quickly)

If any of these persist or you consider them severe then inform doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

  • Allergic reaction (a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue)
  • Skin problems, including blistering or peeling of the skin, or severe blistering rash in which layers of the skin may peel off to leave large areas of raw exposed skin over the body, or skin lesions with a pink/red ring and a pale centre, more sensitive to the sun than usual
  • Slow or uneven heartbeat
  • Very fast, uneven or forceful heartbeat (palpitations)
  • Shortness of breath, feeling tired along with swollen ankles and legs (possible signs of heart failure)
  • Unusual movements of the tongue, muscle spasms in your face, rolling eyes and trembling
  • High temperature, feeling tired, loss of appetite, stomach pain, feeling sick (possible signs of a liver problem, hepatitis)
  • Breast enlargement in men

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

DILTIAZEM PRECAUTIONS

Before taking diltiazem, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: an allergic (hypersensitivity) to diltiazem, you are pregnant or breastfeeding, taking dantrolene, a medicine used for severe muscle spasms or severe fever, acute porphyria, you have a very slow heartbeat - less than 50 beats per minute, heart failure and problems with blood flow to your lungs, or any other serious problems with your heart, including an uneven heartbeat (unless you have a pacemaker).

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: kidney disease, liver disease, any other problem with your heart, apart from angina, or you are going to have an operation with a general anaesthetic.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol intake is not known to affect diltiazem.

The elderly: diltiazem should be used with caution in the elderly and it is usually given at a lower dose.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Diltiazem is not safe to take if you are, or are planning to become, pregnant.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Diltiazem is not safe to take if you are breastfeeding

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

DILTIAZEM INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

There are medicines that are known to interact with diltiazem and your doctor may well have considered this, however if you are taking any of the following medicines please make sure your doctor or pharmacist is aware of this. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • dantrolene infusion

If you are currently using any of these medications, tell your doctor or pharmacist before starting diltiazem.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

This information does not contain all possible interactions. Therefore, before using diltiazem, tell your doctor or pharmacist of all the products you use.

DILTIAZEM OVERDOSE

If you take more tablets than you should, tell a doctor or go to a hospital casualty department straight away. Take the medicine pack with you. This is so the doctor knows what you have taken. The following effects may happen: feeling dizzy or weak, blurred vision, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of diltiazem or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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