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Terms Of Use

FELODIPINE (CARDIOPLEN XL)

Brand Name(s) : Cardioplen XL, Felotens XL, Plendil, Vascalpha
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

FELODIPINE WARNINGS

Felodipine should be used with caution in:
liver problems, stable heart failure, kidney problems; fast heart beat (tachycardia); narrowing (stenosis) of the aorta or of the heart valves (mitral or aortic valve); patients with conduction disturbances in the heart (2nd or 3rd degree atrioventricular block); low blood pressure with abnormal rapid heartbeats; poorly functioning left ventricle of the heart, acute porphyria;.

It should not be used in:
children, unstable angina (chest pain caused by coronary heart disease); untreated heart failure causing swelling of the extremities, weakness and shortness of breath; significant narrowing of the aortic valve in your heart; within 1 month of a heart attack; very low pulse and blood pressure (cardiogenic shock); enlarged heart muscle (hypertrophic cardiomyopathy); other severe heart problems; if your angina has become worse or more frequent; pregnancy or breastfeeding; allergy to felodipine or to any of the ingredients or other calcium-channel blockers (e.g. amlodipine, nisoldipine or nifedipine).

Also see list of precautions and interactions

STORAGE

Do not store the tablets above 25°C.

FELODIPINE USES

Felodipine is used to relax and widen your blood vessels.

It is a dihydropyridine-type calcium-channel blocker, sometimes known as a calcium-channel blocker.

It is used to lower blood pressure and reduce the risk of angina (chest pain caused by lack of blood to the heart).

In general this drug is used to treat high blood pressure and prevent angina attacks.

Benefits of being on this drug can include lowering of arterial blood pressure, prevention of angina.

Listed below are the typical uses of felodipine.

HOW TO USE/TAKE

How often do I take it?

  • Take your felodipine tablets at the same time each day, preferably in the morning on an empty stomach or after a light meal, this medication should not be taken with a high fat meal. Your tablets must be swallowed whole with a glass of water and not with grapefruit juice, as it affect the way felodipine works. Do not break or chew your tablets.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take up to 2 hours before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Felodipine may cause dizziness or tiredness, especially after treatment has just started, or after an increase in your dose. If affected you should not drive or operate machinery. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

FELODIPINE SIDE EFFECTS

  • headache,
  • tinnitus,
  • chest pain or worsening of chest pain,
  • swelling of extremities, in particular ankle swelling,
  • palpitations,
  • dizziness,
  • fatigue,
  • inflammation or welling of the gums,
  • aggravation of angina,
  • pins and needles,
  • restlessness,
  • flushing,
  • fast heart best,
  • very low blood pressure,
  • fainting,
  • shortness of breath,
  • nausea/vomiting,
  • diarrhoea,
  • constipation,
  • itching skin,
  • hives,
  • rash,
  • sensitivity to light,
  • increased sweating,
  • joint or muscle pain,
  • tremors,
  • increased need to pass urine,
  • weight gain.

If you develop any of these symptoms then inform your doctor or pharmacist.

Stop taking your medication and tell your doctor if you develop an allergic reaction or experience chest pain with dizziness.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

FELODIPINE PRECAUTIONS

Before taking felodipine, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: unstable angina (chest pain caused by coronary heart disease); untreated heart failure causing swelling of the extremities, weakness and shortness of breath; significant narrowing of the aortic valve in your heart; within 1 month of a heart attack; very low pulse and blood pressure (cardiogenic shock); enlarged heart muscle (hypertrophic cardiomyopathy); other severe heart problems; if your angina has become worse or more frequent; pregnancy or breastfeeding; allergy to any of the ingredients or other calcium-channel blockers (e.g. amlodipine, nisoldipine or nifedipine).

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: liver problems, stable heart failure, kidney problems; fast heart beat (tachycardia); narrowing (stenosis) of the aorta or of the heart valves (mitral or aortic valve); patients with conduction disturbances in the heart (2nd or 3rd degree atrioventricular block); acute porphyria; low blood pressure with abnormal rapid heartbeats; poorly functioning left ventricle of the heart.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Moderate amounts of alcohol may not affect felodipine, however you should check with your doctor if drinking is advisable.

The elderly: felodipine can be used in the elderly.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Felodipine is not safe to take if you are, or are planning to become, pregnant.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Felodipine is not safe to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

FELODIPINE INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • cimetidine, to treat stomach ulcers;
  • the antibiotics erythromycin, clarithromycin, or telithromycin, to treat bacterial infections;
  • medicines to treat fungal infections: fluconazole, itraconazole, ketoconazole, miconazole, or voriconazole;
  • tacrolimus, ciclosporin, used after kidney or liver transplants;
  • any other medicines that lower blood pressure such as hydrochlorothiazide, beta blockers (to treat high blood pressure), nitrates (to control coronary heart disease and chest pain), phenothiazines (to treat psychoses);
  • phenytoin, carbamazepine or phenobarbital, to treat seizures or epilepsy,
  • amiodarone, diltiazem or verapamil (to treat heart problems),
  • digoxin (to treat heart failure),
  • rifampicin or rifabutin (to treat tuberculosis),
  • fluoxetine or fluvoxamine (to treat depression),
  • phenobarbital, phenytoin, or carbamazepine (to treat epilepsy),
  • cimetidine (to treat heartburn and stomach ulcers),
  • nevirapine, ritonavir, saquinavir, tritonavir
  • herbal medicines containing St. John’s wort (hypericum perforatum).

This information does not contain all possible interactions. Therefore, before using felodipine, tell your doctor or pharmacist of all the products you use.

FELODIPINE OVERDOSE

Do not take more tablets than your doctor tells you to. If you take too many go to the nearest hospital casualty department or tell your doctor immediately. Take the container and any remaining tablets with you to show to the doctor. An overdose may lead to light-headedness, fainting and dizziness caused by very low blood pressure and in rare cases slowed heartbeat (bradycardia).

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of felodipine or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

If you are worried ask you doctor or pharmacist for advice.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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