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Terms Of Use

HALOPERIDOL

Brand Name(s) : Dozic, Haldol, Serenace
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

HALOPERIDOL WARNINGS

Haloperidol should be used with caution in:

  • liver disease,
  • kidney failure,
  • epilepsy and conditions pre-disposing to epilepsy (eg alcohol withdrawal and brain damage) or convulsions,
  • heart problems or family history of heart problems,
  • cardiovascular disease,
  • hardening of the arteries,
  • patients who have had bleeding on the brain, or is at risk of stroke,
  • depression,
  • lower than normal levels of calcium, potassium or magnesium in your blood
  • starvation,
  • alcohol abuse,
  • concomitant therapy with other drugs,
  • problems with your thyroid gland,
  • patients who metabolise some drugs slower than other people,
  • the presence of a non-cancerous tumour of the adrenal gland (phaeochromocytoma).

It should not be used in:

  • patients allergic to haloperidol, or any of the ingredients,
  • heart disease which causes your heart to beat with an abnormal rhythm (arrhythmia) or unusually slowly, with any medicines that affect your heart beat,
  • patients with low levels of potassium in your blood,
  • Parkinson's disease,
  • CNS depression,
  • patients with a condition affecting part of their brain called the 'basal ganglia'
  • patients who are less aware of things around them or whose reactions become slower,
  • patients in a coma.

Also see list of precautions and interactions

STORAGE

Do not store above 25°C.
Do not refrigerate or freeze the medicine.

HALOPERIDOL USES

What is it used for?

  • Haloperidol is used to treat illnesses that affect the way you think, feel or behave.
  • It is a neuroleptic, which is a type of antipsychotic drug.
  • It is used to improve the symptoms of behavioural and mental disorders.

Listed below are the typical uses of haloperidol.
In adults:

  • Schizophrenia
  • Feeling unusually suspicious (paranoia)
  • Mania and hypomania
  • Mental or behavioural problems such as aggression, hyperactivity, agitation
  • As an add-on therapy in the short term management of moderate to severe psychomotor agitation, excitement, violent or dangerously impulsive behaviour
  • Restlessness and agitation in the elderly
  • Anxiety (short-term use)

In children

  • Childhood behavioural disorders especially when associated with hyperactivity and aggression,
  • Childhood schizophrenia

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • Persistent hiccups
  • Nausea and vomiting
  • Gilles de la Tourette Syndrome and severe tics (movements you can't control)

HOW TO USE/TAKE

How often do I take it?

  • Always use haloperidol exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Your doctor will tell you how much haloperidol to take and for how long. Your doctor will adjust the dose to suit you. It is very important you take the correct amount.
  • Take this medication orally, if in tablet formation take with water. If you are prescribed the haloperidol injection, your doctor or nurse will inject it for you.
  • Use this medication as instructed by your doctor in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take some time before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • This medicine may affect your ability to drive. It may make you feel drowsy or dizzy or give you blurred vision. Do not drive or use any tools or machines without discussing this with your doctor first. Consult your doctor or pharmacist for more details.

When can I stop?

  • Take the medicine for as long as your doctor has told you. It may be some time before you feel the full effect of the medicine.
  • Unless your doctor tells you otherwise, you should stop taking haloperidol gradually. Stopping treatment suddenly may cause effects such as: feeling sick (nausea) or being sick (vomiting), difficulty sleeping
  • Always follow your doctor's instructions carefully.

HALOPERIDOL SIDE EFFECTS

  • Sudden swelling of the face or throat,
  • hives,
  • severe irritation,
  • reddening or blistering of the skin,
  • weakness,
  • drowsiness,
  • dizziness,
  • restlessness,
  • difficulty in sleeping,
  • blurred vision,
  • muscle weakness,
  • faintness on standing up,
  • water retention causing swelling or confusion,
  • unexplained bruising or skin rashes (including increased sensitivity to the sun),
  • fast or irregular heartbeat,
  • constipation,
  • difficulty or inability to pass urine,
  • high temperature,
  • breast enlargement in men,
  • inappropriate milk production,
  • altered menstrual cycle (e.g. periods stop),
  • feeling slowed down,
  • agitation,
  • more saliva being produced than normal,
  • effects on muscle control, including slurred speech, odd movements of the face, particularly of the tongue, eyes, head or neck (such as twisting of the neck which causes an unnatural positioning of the head), rigid muscles, tremors, restlessness and difficulty in sitting still. Other muscle control problems include uncontrollable movements of the arms and legs constant chewing or tongue movements or other gentle movements of the neck, head or trunk.
  • Neuroleptic Malignant Syndrome: this causes a high temperature, rigid muscles, drowsiness, occasional loss of consciousness, and can be very serious,
  • if you have angina and your pain is getting worse
  • jaundice (yellowing of skin and whites of eyes),
  • eye problems,
  • skin colouring (pigmentation),
  • blood problems,
  • sore throat,
  • high fever,
  • tiredness,
  • become pale,
  • develop bruises,
  • nose bleeds.
If any of these persist or you consider them severe then inform your doctor.

Tell your doctor immediately if you develop any of the following symptoms:

  • Sudden swelling of the face or throat. Hives (also known as nettle rash or urticaria), severe irritation, reddening or blistering of your skin. These may be signs of a severe allergic reaction.
  • A serious problem called ‘neuroleptic malignant syndrome’. The signs may include: fast heart beat, changing blood pressure and sweating followed by fever; faster breathing, muscle stiffness, reduced consciousness and coma; raised levels of a protein in your blood (an enzyme called creatine phosphokinase);
  • Abnormal heartbeat (arrhythmia);
  • Jerky movements and problems such as slowness, muscle stiffness, trembling and feeling restless. More saliva than normal, twitching or unusual movements of the tongue, face, mouth, jaw or throat, or rolling of the eyes. If you get any of these effects, you may be given an additional medicine.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website

HALOPERIDOL PRECAUTIONS

Before taking haloperidol, tell your doctor or pharmacist if you are allergic to it; or to other similar (neuroleptic) medicines; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • allergies to haloperidol, or any of the ingredients,
  • heart disease which causes your heart to beat with an abnormal rhythm (arrhythmia) or unusually slowly,
  • with any medicines that affect your heart beat,
  • patients with low levels of potassium in your blood,
  • Parkinson's disease,
  • patients with a condition affecting part of their brain called the 'basal ganglia'
  • patients who are less aware of things around them or whose reactions become slower,
  • patients in a coma.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following:

  • liver disease,
  • kidney failure,
  • epilepsy and conditions pre-disposing to epilepsy (eg alcohol withdrawal and brain damage) or convulsions,
  • heart problems or family history of heart problems,
  • cardiovascular disease,
  • hardening of the arteries,
  • patients who have had bleeding on the brain, or are at risk of stroke,
  • depression,
  • lower than normal levels of calcium, potassium or magnesium in your blood
  • starvation,
  • alcohol abuse,
  • concomitant therapy with other drugs,
  • problems with your thyroid gland,
  • patients who metabolise some drugs slower than other people,
  • the presence of a non-cancerous tumour of the adrenal gland (phaeochromocytoma).

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Drinking alcohol while you are taking haloperidol tablets might make you feel drowsy and less alert. This means you should be careful how much alcohol you drink.

The elderly: haloperidol can be used in the elderly.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Do not take haloperidol if you are pregnant, think you may be pregnant or are planning to become pregnant, unless your doctor decides that treatment is essential. It is particularly important not to take haloperidol during the first three months of pregnancy. Ask your doctor or pharmacist for advice before taking any medicine

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Do not take haloperidol if you are breast feeding, unless your doctor decides that treatment is essential.
Ask your doctor or pharmacist for advice before taking any medicine.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

HALOPERIDOL INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • drugs that affect the beating of your heart, for example, verapamil, sotalol, amiodarone.

If you are currently using any of these medications, tell your doctor or pharmacist before starting haloperidol.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • sleeping tablets (tranquillisers),
  • strong pain killers (e.g. codeine),
  • medicines which result in lowering of blood pressure (e.g. methyldopa, guanethidine, diuretics),
  • medicines for asthma or to relieve a stuffy nose (adrenaline or sympathomimetic drugs),
  • antidepressants (e.g. lithium),
  • medicines for fits (anticonvulsants),
  • medicines for Parkinson’s disease (e.g. levodopa),
  • medicines that thin the blood (e.g. phenindione),
  • tricyclic antidepressants (used to calm emotions and bring about sleep),
  • selective serotonin re-uptake inhibitors (SSRIs) - e.g. fluoxetine or fluvoxetine,
  • phenindione - for thrombosis and thinning the blood,
  • adrenaline - for severe allergic reaction,
  • anticonvulsants - in particular phenobarbital and carbamazepine for epilepsy,
  • medicines for anxiety (e.g. buspirone),
  • medicines for problems with your heart beat, such as quinidine,
  • rifampicin (serious infections).

This information does not contain all possible interactions. Therefore, before using haloperidol, tell your doctor or pharmacist of all the products you use.

HALOPERIDOL OVERDOSE

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of haloperidol or intentional overdose is suspected, immediately contact your local hospital, GP or if in England call 111 or NHS Direct. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, do not take the dose you have missed. Then resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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