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Terms Of Use

AMISULPRIDE

Brand Name(s) : Solian
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

AMISULPRIDE WARNINGS

Amisulpride should be used with caution in:

It should not be used in:

  • patients who are allergic (hypersensitive) to amisulpride or any of the other ingredients
  • women who are pregnant, at risk of becoming pregnant, or who are breast-feeding
  • patients with breast cancer or prolactin dependent tumours
  • patients with a tumour on their adrenal gland (called phaeochromocytoma)
  • patients taking levodopa, a medicine used to treat Parkinson's disease
  • children before the onset of puberty

Also see list of precautions and interactions.

STORAGE

Amisulpride tablets should be disposed of if they become discoloured.

Amisulpride solution should be discarded 2 months after opening.

AMISULPRIDE USES

What is it used for?

  • Amisulpride is used to treat schizophrenia.
  • It is an atypical antipsychotic medicine, sometimes called second-generation antipsychotic.
  • It is used to treat disturbed thoughts, feelings and behaviour.
  • In general this drug is used to treat schizophrenia when it first starts, and as long-term treatment for this mental condition.
  • Benefits of being on this drug can include relief from the symptoms of schizophrenia, which include: feeling, seeing or hearing things which do not exist; having strange and frightening thoughts; changing how you act; making you feel alone, tense, anxious or depressed.

Listed below are the typical uses of amisulpride.

  • acute schizophrenia (short term)
  • chronic schizophrenia (long term)

HOW TO USE/TAKE

How often do I take it?

  • Take this medication orally exactly as your doctor has told you.
  • Take the tablet form of this medicine before a meal, swallowing tablets whole with a glass of water.
  • Take the liquid form of this medicine with a drink that does not contain alcohol, and use a graduated syringe to measure the medicine.

Use this medication regularly in order to get the most benefit from it.

Remember to use it at the same time each day - unless specifically told otherwise by your doctor.

Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • You may feel less alert, drowsy or sleepy whilst taking this medicine. If this happens, do not drive or use any tools or machines. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

AMISULPRIDE SIDE EFFECTS

  • Trembling
  • Muscle stiffness
  • Uncontrolled movements (spasms)
  • Slow movement
  • Producing more saliva than usual
  • Feeling restless.
  • Movements that cannot be controlled in the arms and legs
  • Movements that cannot be controlled in the face or tongue

Tell your doctor immediately if you develop any of the above symptoms.

If any of these persist or you consider them severe then inform your doctor:

If any of these persist or you consider them severe then inform your doctor or pharmacist.

Stop taking amisulpride and see a doctor or go to a hospital straight away if you develop any of the following:

  • A high temperature, sweating, stiff muscles, fast heartbeat, fast breathing and feel confused, drowsy or agitated. These could be the symptoms of a serious but rare side effect called ‘neuroleptic malignant syndrome’; an unusual heart rate, very fast heart rate or chest pain which could result in a heart attack or life-threatening heart disorder; fits (seizures); swelling, pain and redness in the legs which may be symptoms of blood clots in the legs which can travel through blood vessels to the lungs causing chest pain and difficulty in breathing.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

AMISULPRIDE PRECAUTIONS

Before taking amisulpride, tell your doctor or pharmacist if you are allergic to it; or to another antipsychotic; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of:

  • an allergy (hypersensitivity) to amisulpride or any of the other ingredients
  • pregnancy, breastfeeding, or being at risk of becoming pregnant
  • breast cancer or prolactin dependent tumours
  • tumour on the adrenal gland (called phaeochromocytoma)
  • taking levodopa, a medicine used to treat Parkinson's disease
  • children before the onset of puberty .

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following:

  • the presence of diabetes, or being at risk of developing diabetes
  • kidney problems
  • history of epilepsy
  • Parkinson's disease
  • heart disease, or a family history of heart disease
  • blood clots or a family history of blood clots
  • unusual or slow heart rate
  • decreased levels of potassium in your blood
  • previous stroke, or risk of having a stroke.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Do not drink alcohol while taking amisulpride.

The elderly: amisulpride should be used with caution in the elderly as it may cause low blood pressure or sleepiness.

Pregnancy and breastfeeding - please ensure you read the detailed information below.

PREGNANCY

Amisulpride is not safe to take if you are, or are planning to become, pregnant.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Amisulpride is not safe to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

AMISULPRIDE INTERACTIONS

Before using this medicine, tell your prescriber of all the medicines you are taking including prescription medicines and medicines you have bought over the counter without a prescription. Tell your prescriber if you are taking vitamins or complementary remedies such as herbal products, as these can also interact with medicines.

If you are taking more than one medicine, these may interact with each other. Your prescriber may decide to use medicines which interact with each other if the benefit outweighs the risks. In these cases, the dose of your medicines may need to be adjusted or you may be monitored more closely.

The following medicines may interact with amisulpride:

  • Levodopa
  • Droperidol
  • Erythromycin
  • Methadone
  • Pentamidine isetionate
  • Dopamine agonists such as bromocriptine and ropinirole
  • Medicines used to control the heart beat, such as amiodarone, quinidine, disopyramide and sotalol
  • Other anti-psychotic medicines used to treat mental problems
  • Opiates such as morphine and pethidine
  • Medicines to treat heart problems such as diltiazem, verapamil, digitalis
  • Clonidine used for migraines, flushing or high blood pressure
  • Diuretics
  • Mefloquine used to treat malaria
  • Barbiturates
  • Benzodiazepines
  • Painkillers such as tramadol and indometacin
  • Anaesthetics
  • Sedative antihistamines
  • This information does not contain all possible interactions. Therefore, tell your prescriber of all the products you are using before taking this medicine.

    If you have a question or want to discuss anything about your medicine, speak to your local pharmacist.

    AMISULPRIDE OVERDOSE

    If you think you, or someone you care for, might have accidentally taken more than the recommended dose of amisulpride or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

    MISSED DOSE

    If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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    Source: Selected from data included with permission and copyrighted by Boots UK Limited. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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