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LORMETAZEPAM

Brand Name(s) : None
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

LORMETAZEPAM WARNINGS

Lormetazepam should be used with caution in: the elderly, women who are pregnant or who are breastfeeding, patients with long-term liver or kidney problems, depression or anxiety with depression, respiratory diseases, personality disorders, and a history of stroke.

It should not be used in: children, patients with severe respiratory depression (when breathing is slower an/or less deep than normal), those with myasthenia gravis (a muscle weakness disease), acute pulmonary insufficiency (failure of the pulmonary valve in the heart, permitting blood to back-flow into the right ventricle), sleep apnoea syndrome (when breathing stops temporarily when asleep), a phobia (irrational fear of something), an obsession or chronic psychosis, monotherapy (when given alone) in depression or anxiety with depression, current or previous alcoholism.

Also see list of precautions and interactions.

STORAGE

Protect from light and store in a dry place below 25°C.

LORMETAZEPAM USES

What is it used for?

  • Lormetazepam is used to treat sleeplessness (insomnia).
  • It is a tranquilliser (medicine that has a calming effect), sometimes known as sedatives or sleeping pills.
  • It is used to treat insomnia.
  • In general this drug is used to treat sleeplessness (insomnia), but only in the short term where the insomnia is severe, disabling or distressing.
  • Benefits of being on this drug can include relief from insomnia.

Listed below are the typical uses of lormetazepam.

  • Short-term treatment of insomnia (including difficulty falling asleep and/or frequent awakenings at night), when insomnia is severe, disabling or causing distress.

On occasion your doctor may prescribe this medicine to treat a condition not on the above list.

HOW TO USE/TAKE

How often do I take it?

  • Take this medication by mouth, usually once-daily before going to bed. Swallow tablets whole, and take with a drink of water.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take a while before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • You may need to avoid driving or operating machinery as this medication may make you sleepy or forgetful, cause muscle weakness, and you may feel less alert than normal. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

LORMETAZEPAM SIDE EFFECTS

This is not a complete list of possible side effects. If any of these persist or you consider them severe then inform your doctor.

Tell your doctor immediately if you develop any of the following symptoms: amnesia, dependence (addiction), feeling depressed and/or having thoughts of self harm or suicide, or limp or weak muscles.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

LORMETAZEPAM PRECAUTIONS

Before taking lormetazepam, tell your doctor or pharmacist if you are allergic to it, to other sedative drugs; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe respiratory depression (when breathing is slower an/or less deep than normal), myasthenia gravis (a muscle weakness disease), acute pulmonary insufficiency (failure of the pulmonary valve in the heart, permitting blood to back-flow into the right ventricle), sleep apnoea syndrome (when breathing stops temporarily when asleep), a phobia (irrational fear of something), an obsession or chronic psychosis, in depression or anxiety with depression (when given as monotherapy), current or previous alcoholism.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: any liver or kidney problems, heart conditions or mental illnesses, sleep disorders, or a history of alcohol or drug abuse.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol should be avoided as it may intensify side-effects such as drowsiness brought about by lormetazepam, and may be very dangerous.

The elderly: lormetazepam should be used with caution in the elderly as it may worsen side-effects caused by lormetazepam, such as confusion or lack of co-ordination.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

The safety of lormetazepam has not been established during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.
First trimester: avoid
Second trimester: not recommended
Third trimester: avoid.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Lormetazepam is not safe to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist

.

LORMETAZEPAM INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • Sodium oxybate used to treat muscular weakness (cataplexy) associated with extreme sleepiness (narcolepsy).

If you are currently using any of these medications, tell your doctor or pharmacist before starting lormetazepam.

  • Other tranquillisers or sleeping pills, or other such medicines that act on the brain and nerves
  • Antidepressants (e.g. tricyclic antidepressant, such as such as amitriptyline or clomipramine; mirtazapine)
  • General anaesthetics and painkillers (narcotic analgesics for moderate-to-severe pain, such as codeine, methadone, morphine, oxycodone, pethidine or tramadol)
  • Antihistamines (used for treating allergies) that cause drowsiness (e.g. chlorphenamine or promethazine)
  • Antibiotics (e.g. rifampicin)
  • Antivirals (e.g. ritonavir).

This information does not contain all possible interactions. Therefore, before using lormetazepam, tell your doctor or pharmacist of all the products you use.

LORMETAZEPAM OVERDOSE

Overdosage does not usually present a threat to life.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of lormetazepam or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

Lormetazepam must only be taken at bedtime. If you forget to take your tablet at bedtime, then you should not take it at any other time, otherwise you may feel drowsy, dizzy and confused during the day. Do not take a double dose to make up for a forgotten dose.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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