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AMOXICILLIN

Brand Name(s) : Amoxil, Amix, Amoram, Amoxident, Galenamox, Rimoxallin, Augmentin in combination with clavulanic acid (co-amoxiclav), Augmentin-Duo in combination with clavulanic acid (co-amoxiclav)
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

AMOXICILLIN WARNINGS

Amoxicillin should be used with caution in: patients who have any allergies, those with kidney problems, glandular fever (a virus infection which causes a sore throat, high temperature above 39°C or 102.2°F, tiredness, muscle pains and headache), or those who are not well hydrated (not passing water regularly).

It should not be used in: patients who are described as hypersensitive (allergic) to penicillin (amoxicillin belongs to the class of antibiotics called penicillins).

Also see list of precautions and interactions.

STORAGE

Store below 25°C.

AMOXICILLIN USES

Amoxicillin is used to treat a number of problems.

It is a member of a class of drugs called broad-spectrum penicillins, which are themselves part of a larger group of drugs called antibiotics.

In general, this drug is used to treat infections caused by bacteria.

Benefits of being on this drug include the eradication, control or prevention of bacterial infections that may otherwise be harmful.

Listed below are the typical uses of amoxicillin:

  • Treating infections (caused by bacteria) in many different parts of the body.
  • To prevent bacterial infections happening in some situations (e.g. when you have a tooth removed or another form of surgery)
  • In combination with other medicines (termed proton pump inhibitors, or PPIs) it can be used to treat stomach ulcers.

On occasion your doctor may prescribe this medicine to treat a condition not on the above list

HOW TO USE/TAKE

How often do I take it?

  • This medication is available as a capsule, a powder for adding to water, or as a suspension, all of which should be taken orally, before, during, or after eating and several times per day. Tablets should be taken with a glass of water. This medication is also available as an injection
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take some time before you notice any benefits of this drug.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy and use of certain interacting medicines.

Do I need to avoid anything?

When can I stop?

  • Always complete the full course as prescribed by your doctor.

AMOXICILLIN SIDE EFFECTS

If any of these persist or you consider them severe then inform your doctor.

Tell your doctor immediately if you develop any of the following symptoms: erythema multiforme (itchy, reddish-purple patches of skin, especially on the palms and soles of the feet, raised swollen areas of skin, tender areas in the mouth, eyes or private parts, fever and tiredness); rash or pinpoint flat red round spots under the skin; unexplained bruising of the skin; high fever; inflammation of the large bowel (colon), with diarrhoea containing blood, pain and fever; enlargement of the lymph nodes, especially under the arms; serious liver side effects (severe diarrhoea with bleeding, blisters, redness or bruising of the skin, darkened urine or paler stools, and yellowing of the skin or the whites of the eyes).

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

AMOXICILLIN PRECAUTIONS

Before taking amoxicillin, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics; or if you have any other allergies.

Before taking amoxicillin, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: an allergy (hypersensitivity) to penicillin or amoxicillin.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: any previous allergic reaction to any antibiotic. This can include a skin rash or swelling of the face or neck when taking an antibiotic.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol intake is not known to affect amoxicillin.

Pregnancy and breastfeeding - please ensure you read the detailed information below.

PREGNANCY

Amoxicillin is suitable to take during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Amoxicillin is excreted in breast milk in very small quantities but is considered suitable to take if you are breastfeeding. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

AMOXICILLIN INTERACTIONS

Before using this medicine, tell your prescriber of all the medicines you are taking including prescription medicines and medicines you have bought over the counter without a prescription. Tell your prescriber if you are taking vitamins or complementary remedies such as herbal products, as these can also interact with medicines.

If you are taking more than one medicine, these may interact with each other. Your prescriber may decide to use medicines which interact with each other if the benefit outweighs the risks. In these cases, the dose of your medicines may need to be adjusted or you may be monitored more closely.

The following medicines may interact with amoxicillin:

This information does not contain all possible interactions. Therefore, tell your prescriber of all the products you are using before taking this medicine.

If you have a question or want to discuss anything about your medicine, speak to your local pharmacist.

AMOXICILLIN OVERDOSE

Symptoms of an overdose include: feeling sick (nausea), vomiting, diarrhoea, and sometimes amoxicillin crystalluria (crystals in the urine, which appears cloudy, and can lead to kidney failure).

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of amoxicillin or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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