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Terms Of Use

ARIPIPRAZOLE

Brand Name(s) : Abilify
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

ARIPIPRAZOLE WARNINGS

Aripiprazole should be used with caution in:

  • the elderly
  • patients with high blood sugar levels (diabetes) or a family history of diabetes
  • patients who are overweight or suffer from fitting (seizures)
  • involuntary, irregular muscle movements particularly in the face
  • heart disease or have a family history of heart disease
  • patients with abnormal blood pressure or who have had a stroke or mini stroke
  • patients with depression
  • patients with severe liver disease
  • patients with an enlarged prostate
  • patients with an intolerance to certain sugars
  • patients with blood clots or family history of blood clots
  • patients at risk of aspiration pneumonia (a type of pneumonia caused by the entry of foreign material into the lungs).

It should not be used in:

  • children or adolescents aged under 15 years of age
  • patients who are allergic to aripiprazole or to any other ingredients in the medicine
  • patients with a tumour on their adrenal gland (called phaeochromocytoma)
  • patients taking the medicines artemether/lumefantrine, pramipexole, ropinirole, or rotigotine.

Also see list of precautions and interactions

STORAGE

Store in the original package.

ARIPIPRAZOLE USES

What is it used for?

  • Aripiprazole is used to treat the psychiatric disorders schizophrenia and mania.
  • It is an atypical antipsychotic, sometimes known as an antipsychotic.
  • It is used to treat adults who have schizophrenia which is a disease characterised by symptoms such as hearing, seeing or sensing things which are not there, suspiciousness, mistaken beliefs, speech that cannot be understood, flatness in behaviour and emotions, feeling depressed, guilty, anxious or tense. It is also used to treat mania a condition with symptoms such as feeling high, having excessive amounts of energy, needing much less sleep than usual, talking very quickly with racing ideas, sometimes with severe irritability. Aripiprazole can also be used long term to stabilise mood and prevent further manic episodes in patients who have already responded to aripiprazole. Aripiprazole works by acting on various receptors in the brain including dopamine receptors and serotonin (5HT) receptors.
  • In general this drug is used to control and treat agitation and disturbed behaviour in patients with schizophrenia or mania.
  • Benefits of being on this drug can include relief from the symptoms of schizophrenia and mania.

Listed below are the typical uses of aripiprazole.

  • Schizophrenia
  • Mania

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • None known.

HOW TO USE/TAKE

How often do I take it?

  • Take this medication by mouth usually once a day, with or without food. Take the tablet with water and swallow it whole. You may have been prescribed special tablets which can be dispersed in water and swallowed, or placed on the tongue and allowed to dissolve. Alternatively, your doctor may have prescribed you aripiprazole liquid. This should not be diluted with other liquids or mixed with any foods before taking. Make sure you read the patient information leaflet carefully before taking your medicine. If you are unsure how to take your medicine contact your doctor or pharmacist.
  • Other formulations may need to be taken more or less frequently as indicated by your doctor or pharmacist.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told not to by your doctor.
  • It may take up to several days or some weeks before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Aripiprazole may make you feel drowsy. You should not drive or operate machinery until you know how aripiprazole affects you. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

ARIPIPRAZOLE SIDE EFFECTS

If any of these persist or you consider them severe then inform your doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Further information about other side effects can be found in the patient information leaflet.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

ARIPIPRAZOLE PRECAUTIONS

Before taking aripiprazole tell your doctor or pharmacist if you are allergic to it; or to other antipsychotics; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of: an allergy to aripiprazole or to any other ingredients in the medicine, a tumour on the adrenal gland (called phaeochromocytoma), you are taking the medicines artemether/lumefantrine, pramipexole, ropinirole, or rotigotine.

Before using this medication tell your doctor or pharmacist your medical history, especially any of the following high blood sugar levels (diabetes) or a family history of diabetes, you are overweight or suffer from fitting (seizures), you have involuntary, irregular muscle movements particularly in the face, you have heart disease or have a family history of heart disease, you have abnormal blood pressure or have had a stroke or mini stroke, have severe liver disease, an intolerance to certain sugars, have depression, an enlarged prostate, you are at risk of aspiration pneumonia (a type of pneumonia caused by the entry of foreign material into the lungs).

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • You should not drink alcohol while taking aripiprazole.

The elderly: aripiprazole should be used with caution in the elderly as it may be associated with a high incidence of side effects in older patients.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Aripiprazole is not safe to take if you are, or are planning to become, pregnant.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Aripiprazole is not safe to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

ARIPIPRAZOLE INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • Artemether/lumefantrine
  • Pramipexole
  • Ropinirole
  • Rotigotine

If you are currently using any such medicine, tell your doctor or pharmacist before starting aripiprazole.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • ACE inhibitor such as captopril
  • Alcohol
  • Alpha blockers such as prazosin
  • Amantadine
  • Anaesthetics
  • Angiotensin II receptor antagonists such as candesartan
  • Apomorphine
  • Atomoxetine
  • Atazanavir
  • Benzodiazepines
  • Barbiturates
  • Bromocriptine
  • Cabergoline
  • Calcium channel blockers such as nifedipine, diltiazem
  • Carbamazepine
  • Cimetidine
  • Efavirenz
  • Escitalopram
  • Ethosuximide
  • Fluoxetine
  • Fosamprenavir
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Levodopa
  • Lopinavir
  • Memantine
  • Methyldopa
  • Metoclopramide
  • Nelfinavir
  • Nevirapine
  • Opioid painkillers
  • Oxcarbazepine
  • Paroxetine
  • Pergolide
  • Phenytoin
  • Phenobarbital
  • Primidone
  • Quinidine
  • Rifampicin
  • Rifabutin
  • Ritonavir
  • Saquinavir
  • Medicines for irregular heart rhythm (anti-arrhythmics)
  • Medicines for depression (antidepressants)
  • Medicines for anxiety
  • Sleeping tablets
  • St John's wort
  • Sodium oxybate
  • Sympathomimetics (often found in cold remedies and asthma medicines)
  • Tetrabenazine
  • Tramadol
  • Valproate

This information does not contain all possible interactions. Therefore, before using aripiprazole, tell your doctor or pharmacist of all the products you use.

ARIPIPRAZOLE OVERDOSE

Taking too much aripiprazole may cause the following: lack of energy, increased blood pressure, drowsiness, increased heart rate, feeling sick and being sick, diarrhoea, uncontrollable twitching or jerking movements and loss of consciousness.

People who have taken too much aripiprazole should contact their doctor straight away. If you cannot reach your doctor, go to the nearest hospital and take the medicine pack with you.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of aripiprazole or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember but do not take two doses in one day.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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