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Terms Of Use

PERINDOPRIL ERBUMINE

Brand Name(s) : None
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

PERINDOPRIL ERBUMINE WARNINGS

Perindopril erbumine should be used with caution in: patients receiving diuretics; peripheral vascular disease or generalised atherosclerosis; collagen vascular disease; severe or symptomatic aortic stenosis (narrowing of the main blood vessels from the heart); hypertrophic cardiomyopathy or renal artery stenosis (narrowing of the blood vessels to the kidneys); a history of heart, liver or kidney problems; diabetic patients; those about to have a general anaesthetic; LDL apheresis patients (which is removal of cholesterol from your blood by a machine); those undergoing desensitisation treatment to reduce the effects of an allergy to bee or wasp stings; those on a salt restricted diet; those who have recently suffered from diarrhoea or vomiting, or are dehydrated; patients with an intolerance to certain sugars; women who are breastfeeding.

It should not be used in: patients who are hypersensitive (allergic) to perindopril or to any other ACE inhibitor; women who are more than 3 months pregnant (it is also better to avoid perindopril in early pregnancy); those with a history of angioedema associated with previous ACE inhibitor therapy; hereditary or idiopathic angioedema.

Also see list of precautions and interactions.

STORAGE

Do not store above 30° C.

PERINDOPRIL ERBUMINE USES

Perindopril erbumine is used to treat conditions that result from problems with circulation of the blood, such as high blood pressure and heart failure.

It is a type of ACE inhibitor, and is used to widen blood vessels, making it easier for the heart to pump blood through the body.

In general, this drug is used to treat high blood pressure, heart failure and to reduce the risk of heart attack, or other cardiac events, in patients with stable coronary artery disease (a condition where the blood supply to the heart is reduced or blocked) and who have already had a heart attack and/or an operation to improve the blood supply to the heart by widening the vessels that supply it.

Benefits of being on this drug include lowered blood pressure and reduction of the risks of cardiac events in patients with stable coronary artery disease who have already had a heart attack and/or an operation to improve the blood supply to the heart by widening the vessels that supply it.

Listed below are the typical uses of perindopril erbumine.

  • High blood pressure (hypertension)
  • Heart failure
  • Reducing of the risk of cardiac events, such as heart attack, in patients with stable coronary artery disease (a condition where the blood supply to the heart is reduced or blocked) and who have already had a heart attack and/or an operation to improve the blood supply to the heart by widening the vessels that supply it.

HOW TO USE/TAKE

How often do I take it?

  • This medication is available as tablets which are taken orally usually with a glass of water, in the morning, before a meal. Your doctor will decide the correct dose for you.
  • Use this medicine regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • If you feel dizzy or tired while taking perinodopril erbumine, avoid driving or using machinery. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

PERINDOPRIL ERBUMINE SIDE EFFECTS

  • Swelling of the face, lips, mouth, tongue or throat, difficulty in breathing
  • Severe dizziness or fainting
  • Unusual fast or irregular heart beat
  • Headache
  • Dizziness
  • Vertigo
  • Pins and needles
  • Vision disturbances
  • Tinnitus (sensation of noises in the ears)
  • Light-headedness due to low blood pressure
  • Cough
  • Shortness of breath
  • Gastro-intestinal disorders (nausea, vomiting, abdominal pain, taste disturbances, dyspepsia or difficulty of digestion, diarrhoea, constipation)
  • Allergic reactions (such as skin rashes, itching)
  • Muscle cramps
  • Feeling of weakness
  • Mood and sleep disturbances.

For less common side effects, please refer to the patient information leaflet.

If any of these persist or you consider them severe then inform your doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms: swelling of the face, lips, mouth, tongue or throat, difficulty in breathing; severe dizziness or fainting; unusual fast or irregular heart beat

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website

PERINDOPRIL ERBUMINE PRECAUTIONS

Before taking perindopril erbumine, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: experienced symptoms such as wheezing, swelling of the face, tongue or throat, intense itching or severe skin rashes with previous ACE inhibitor treatment or if you or a member of your family have had these symptoms in any other circumstances (a condition called angioedema).

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: aortic stenosis (narrowing of the main blood vessel leading from the heart); hypertrophic cardiomyopathy (heart muscle disease); renal artery stenosis (narrowing of the artery supplying the kidney with blood); other heart problems; liver problems; kidney problems or receiving dialysis; a collagen vascular disease such as systemic lupus erythematosus or scleroderma; diabetes; if you are on a salt restricted diet or use salt substitutes which contain potassium; due to undergo LDL apheresis (which is removal of cholesterol from your blood by a machine); desensitisation treatment to reduce the effects of an allergy to bee or wasp stings; recent diarrhoea or vomiting, or are dehydrated; intolerance to some sugars.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • No

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Perindopril erbumine is not safe to take if you are, or are planning to become, pregnant.

First trimester: not recommended
Second trimester: avoid
Third trimester: avoid

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Perindopril erbumine is not recommended if you are breastfeeding

Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

PERINDOPRIL ERBUMINE INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • none known.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Other medicines for high blood pressure such as water tablets (diuretics)
  • Potassium-sparing diuretics (water tablets which affect potassium levels), such as spironolactone, triamterene or amiloride
  • Potassium supplements or potassium containing salt substitutes
  • Lithium for mania or depression
  • Non-steroidal anti-inflammatory painkilling drugs (NSAIDs) such as ibuprofen
  • Medicines for diabetes including insulin
  • Medicines to treat mental disorders such as anxiety, depression and schizophrenia
  • Medicines to suppress the immune system (immunosuppressants such as azathioprine, ciclosporin and cyclophosphamide)
  • Allopurinol to treat gout
  • Heparin used to thin the blood
  • Probenecid for the treatment of an irregular heart beat
  • Medicines for low blood pressure, shock or asthma (including ephedrine,noradrenaline or adrenaline)
  • Medicines that make the blood vessels wider (vasodilators, such as nitrates)
  • This information does not contain all possible interactions. Therefore, before using perindopril erbumine, tell your doctor or pharmacist of all the products you use.

PERINDOPRIL ERBUMINE OVERDOSE

If you take too many tablets, contact your nearest accident and emergency department or tell your doctor immediately. The most likely effect in case of overdose is low blood pressure which can make you feel dizzy or faint. If this happens, lying down with the legs raised can help.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of perindopril erbumine or intentional overdose is suspected, contact your local hospital, GP or if in England call 111 or NHS Direct. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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