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SODIUM CITRATE

Brand Name(s) : Canestan Oasis, Cystocalm, Relaxit Micro-enema (in combination with sodium lauryl sulphate, sorbic acid, sorbitol and glycerol), Micralax Micro-enema (in combination with sodium alkylsulphoacetate), Dioralyte (in combination with rice powder, sodium chloride and potassium chloride), Cymalon (in combination with sodium bicarbonate and sodium carbonate), Peach (in combination with dextrose monohydrate, potassium chloride and sodium chloride)
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

SODIUM CITRATE WARNINGS

Sodium citrate should be used with caution in: the elderly or weak (debilitated) patients.

It should not be used in: patients with inflammatory bowel disease (e.g. ulcerative colitis, a disease of the lower intestine [colon] characterised by open sores [ulcers] with symptoms such as frequent diarrhoea mixed with blood), patients with acute gastrointestinal conditions.

Also see list of precautions and interactions.

STORAGE

Store below 25°C.

SODIUM CITRATE USES

What is it used for?

  • Sodium citrate is used to treat a number of problems.
  • It is an osmotic laxative, which induces a laxative effect (stimulating stool production).
  • It is used to relieve constipation and works (when used as an enema for rectal use) by causing water to be drawn into the lower bowel (colon) to increase the water content and volume of stools, making them softer and easier to pass, relieving constipation. It also used for other purposes when taken by mouth, such as in adult women for the relief of symptoms due to cystitis (inflammation of the bladder owing to an infection of urine in women) where it reduces the acidity of urine, and before general anaesthesia to prevent stomach acid aspiration (inhalation of stomach acid into the airways), which may happen during a surgical operation or in pregnant women during child birth.
  • In general, this drug is used to relieve constipation, treat symptoms of mild cystitis or to prevent stomach acid aspiration during anaesthesia.
  • Benefits of being on this drug can include regular bowel movements, relief from the painful symptoms of cystisis and problems occurring after inhalation of acid stomach contents during surgery.

Listed below are the typical uses of sodium citrate.

  • Relief of constipation, or clearing the bowel before surgery, childbirth or bowel investigations (when used as an enema).

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • Oral use: preventing inhalation of acid stomach contents during surgery or relief of discomfort during mild cystitis in adult women.

HOW TO USE/TAKE

How often do I take it?

  • Take this medication rectally, as required, when used as an enema for constipation. (When used to treat cystitis or to reduce the acidity of the stomach contents before an operation it should be taken by mouth, with water, as required.)
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take 5 to 15 minutes before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • No. Consult your doctor or pharmacist for more details.

When can I stop?

  • Always complete the full course as prescribed by your doctor.

SODIUM CITRATE SIDE EFFECTS

  • Diarrhoea
  • Dehydration.

Only the most common side effects have been listed. If any of these persist or you consider them severe then inform your doctor.

Tell your doctor immediately if you develop any of the following symptoms:

  • prolonged constipation.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website

SODIUM CITRATE PRECAUTIONS

Before taking sodium citrate, tell your doctor or pharmacist if you are allergic to it; or to other laxatives; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: inflammatory bowel disease (such as ulcerative colitis, a disease of the lower intestine [colon] characterised by open sores [ulcers] with symptoms such as frequent diarrhoea mixed with blood), acute gastrointestinal conditions.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: any history of bowel disorders, or bloody stools.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol intake is not known to affect sodium citrate.

The elderly: sodium citrate can be used in the elderly.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Sodium citrate is suitable to take during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Sodium citrate is suitable to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

SODIUM CITRATE INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • None known.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • None known.

This information does not contain all possible interactions. Therefore, before using sodium citrate, tell your doctor or pharmacist of all the products you use.

SODIUM CITRATE OVERDOSE

There are no reports of overdoses with this drug.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of sodium citrate or intentional overdose is suspected, contact your local hospital, GP or if in England call 111 or NHS Direct. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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