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Terms Of Use

SULPIRIDE

Brand Name(s) : Dolmatil, Sulpor
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

SULPIRIDE WARNINGS

Sulpiride should be used with caution in: the elderly, women who are pregnant, patients during excited, agitated or aggressive states, those with kidney or liver problems, heart problems, high blood pressure (hypertension), severe breathing problems, depression, epilepsy, an enlarged prostate, Parkinson's disease, myasthenia gravis (a muscle weakness disease), a history of jaundice (yellowing of the skin or the eyes), if the patient or a family member has ever suffered from an eye condition termed angle-closure glaucoma, and during states of mania or hypomania (over-excited states).

It should not be used in: women who are breastfeeding, patients with acute porphyria (an inherited blood disorder, causing skinblisters, belly pain and brain or nervous system disorders), who are semi-conscious or in a coma (unable to wake), a bone-marrow disorder, a growth on the adrenal gland called a phaeochromocytoma, or those with a hormone (prolactin)-dependent breastcancer.

Also see list of precautions and interactions.

STORAGE

Store below 25°C.

SULPIRIDE USES

What is it used for?

  • Sulpiride is used to treat a psychiatric (mental) illness called schizophrenia.
  • It is an antipsychotic.
  • It is used to calm patients who are mentally disturbed (who have symptoms such as hallucinations (seeing or hearing things which are not there) and delusions (false belief held strongly despite overwhelming evidence that disproves such a belief)), and to restore normal behaviour.
  • In general this drug is used to treat schizophrenia.
  • Benefits of being on this drug can include the management of schizophrenia symptoms, reducing their severity and how often they occur.

Listed below are the typical uses of sulpiride.

  • The treatment of schizophrenia.

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • Treating Tourette syndrome or other abnormal involuntary movement disorders (choreas).

HOW TO USE/TAKE

How often do I take it?

  • Take this medication by mouth, usually twice daily. Tablets should be swallowed with a drink of water. It is also available in liquid form, to be given by mouth.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take some time before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Avoid driving or operating machinery if sulpiride causes drowsiness or makes you feel less alert than normal. Avoidance of excessive exposure to direct sunlight is also recommended. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

SULPIRIDE SIDE EFFECTS

  • Sleepiness
  • Lack of energy
  • Weight gain
  • Constipation
  • Increased or decreased sex drive
  • Impotence and problems ejaculating (in men)
  • Difficulty sleeping
  • Feeling confused
  • Blocked nose
  • Blurred vision
  • Over excitement
  • Agitation
  • Aggression
  • Rashes
  • Pigmentation of the skin or eyes
  • Sensitivity to sunlight.
This is not a complete list of possible side effects. If any of these persist or you consider them severe then inform doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms: high temperature, muscle stiffness, fainting or excessive drowsiness.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

SULPIRIDE PRECAUTIONS

Before taking sulpiride, tell your doctor or pharmacist if you are allergic to it; or to other antipsychotics; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: acute porphyria (an inherited blood disorder, causing skin blisters, belly pain and brain or nervous system disorders), are semi-conscious or in a coma (unable to wake), have a bone-marrow disorder, a growth on the adrenal gland called a phaeochromocytoma, or a hormone (prolactin)-dependent breast cancer.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: any liver or kidney problems, heart problems, high blood pressure, or history of fits, lung diseases or breathing difficulties, or any difficulties in passing water.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • The effects of alcohol can be increased by sulpiride, so avoid or moderate your intake of alcohol.

The elderly: sulpiride should be used with caution in the elderly as they are more likely to have side-effects with this drug than younger patients.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

The safety of sulpiride has not been established during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

First trimester: avoid
Second trimester: not recommended
Third trimester: avoid.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Sulpiride is not safe to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

SULPIRIDE INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • Other antipsychotics (e.g. pimozide or thioridazine)

If you are currently using any of these medications, tell your doctor or pharmacist before starting sulpiride.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Anticonvulsants (e.g. valproate or phenytoin)
  • Painkillers (e.g. opioids such as tramodol) and general anaesthetics
  • Anti-arrhythmics (e.g. amiodarone or disopyramide)
  • Antidepressants (the selective serotonin reuptake inhibitor [SSRI] fluoxetine and tricyclic antidepressants [TCAs] such as amitriptyline)
  • Antiepileptics (e.g. carbamazepine, phenytoin, valproate or primidone)
  • Antihistamines (for the treatment of allergies)
  • Antimalarials (e.g. mefloquine or quinine)
  • Tranquillisers and sleeping tablets (e.g. diazepam).

This information does not contain all possible interactions. Therefore, before using sulpiride, tell your doctor or pharmacist of all the products you use.

SULPIRIDE OVERDOSE

An overdose of sulpiride may cause:
restlessness, lowered state of consciousness, agitation, confusion, extrapyramidal symptoms (abnormal movements of the hands, legs, face, neck and tongue, such as tremor, twitching or rigidity), coma (unable to wake), low blood pressure (hypotension).

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of sulpiride or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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