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Terms Of Use

TRANEXAMIC ACID

Brand Name(s) : Cyklokapron
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

TRANEXAMIC ACID WARNINGS

Tranexamic acid should be used with caution in: the elderly, children aged under 15 years with heavy or prolonged menstrual periods (menorrhagia), kidney disease, patients with blood in their urine, history of uncontrollable bleeding, pregnancy and breastfeeding, patients with the blood clotting disorder disseminated intravascular coagulation (DIC) which is ongoing, increased fibrinolysis (clot breakdown) caused by DIC, long term treatment of the hereditary condition angioneurotic oedema, women with irregular menstrual periods.

It should not be used in: patients with an allergy to tranexamic acid or to any other ingredients in the medicine or patients with an allergy to other anti-fibrinolytics, severe kidney problems (kidney failure), patients who have or have had a blood clot in their blood vessels (thrombosis) particularly in the leg or lung, patients in whom a blood clot has caused a stroke, severe bruising, patients with family members who have had a blood clot in their blood vessels, irregular periods for which the reason is unknown.

Also see list of precautions and interactions

STORAGE

Do not store above 25ºC.

TRANEXAMIC ACID USES

What is it used for?

  • Tranexamic acid is used to prevent or reduce bleeding.
  • It is an anti-fibrinolytic.
  • It is used to stop excessive bleeding after an operation or to help with blood clotting. When you bleed your body forms a blood clot to help the healing process. However, sometimes the blood clots break down and cause too much bleeding and blood loss. By stopping blood clots from dissolving, tranexamic acid reduces bleeding.
  • In general this drug is used to stop bleeding in patients who undergo minor surgery, in patients with the inherited blood clotting disorder haemophilia and in people in whom blood in the whole body starts to clot, also known as disseminated intravascular coagulation. Tranexamic acid can also be used if you have been treated with a medicine to break down blood clots (thrombolytic).
  • Benefits of being on this drug can include reduction in bleeding and blood loss.

Listed below are the typical uses of tranexamic acid.

  • After surgery of the prostate (prostatectomy)
  • After bladder surgery
  • Heavy and prolonged menstrual periods (menorrhagia)
  • Nose bleeds (epistaxis)
  • Surgery of the cervix (conisation of the cervix)
  • Bleeding of the cervix
  • Bleeding caused by inflammation of the colon and bowel Surgery or tooth removal (dental extraction) in patients who bleed more easily than normal (haemophiliacs)
  • Angioneurotic oedema (an inherited disease involving swelling of the skin tissue)
  • On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

    • Disseminated intravascular coagulation (DIC) where blood in the whole body starts to clot
    • After treatment with a medicine to break down blood clots (thrombolysis).

    HOW TO USE/TAKE

    How often do I take it?

    • Take this medication by mouth usually two or three times a day with a glass of water, with or without food. Swallow the tablets whole, do not crush or chew. Other formulations such as tranexamic injection may need to be administered more or less frequently, as indicated by your doctor or pharmacist.
    • Use this medication regularly in order to get the most benefit from it.
    • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
    • It may take up to some hours before the full benefit of this drug takes effect.
    • Certain medical conditions may require different dosage instructions as directed by your doctor.

    What dose?

    • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

    Do I need to avoid anything?

    • Tranexamic acid is known to have no or a very small effect on ability to drive or operate machinery. However, when taking tranexamic acid you should take great care when driving or operating machinery. Consult your doctor or pharmacist for more details.

    When can I stop?

    • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

TRANEXAMIC ACID SIDE EFFECTS

  • Feeling sick
  • Being sick
  • Feeling dizzy
  • Diarrhoea
  • Unexpected pain
  • Eyesight problems (particularly affecting colour vision)
  • Blood clot in the eye (may cause bleeding in the eye, loss of eyesight)
  • Itchy, red or swollen skin
  • Blood clot in the blood vessels (thrombosis)
  • Low blood pressure
If any of these persist or you consider them severe then inform your doctor or pharmacist.

Tell your doctor immediately and stop taking your medicine if you develop any of the following symptoms:

  • Changes in your eyesight
  • An allergic skin reaction
  • Pains in your chest or legs which may be a sign of a blood clot.
  • Unexpected swelling
  • Changes in your colour vision
  • Feeling dizzy

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

TRANEXAMIC ACID PRECAUTIONS

Before taking tranexamic acid, tell your doctor or pharmacist if you are allergic to it; or to other anti-fibrinolytics; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: an allergy to tranexamic acid or to any other ingredients in the medicine or an allergy to other anti-fibrinolytics, severe kidney problems (kidney failure), have or have had a blood clot in your blood vessels (thrombosis) particularly in the leg or lung, have had a blood clot has caused a stroke, severe bruising, have family members who have had a blood clot in their blood vessels, or irregular periods for which the reason is unknown.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following kidney disease, patients with blood in their urine, history of uncontrollable bleeding, pregnancy and breastfeeding, the blood clotting disorder disseminated intravascular coagulation (DIC) which is ongoing, increased fibrinolysis (clot breakdown) caused by DIC, long term treatment of the hereditary condition angioneurotic oedema, irregular menstrual periods.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol intake is not known to affect tranexamic acid.

The elderly: tranexamic acid should be used with caution in the elderly as it may build up in the body of patients with kidney problems. Elderly patients are more likely to have kidney problems than younger patients.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

The safety of tranexamic acid has not been established during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

The safety of tranexamic acid in breastfeeding has not been established.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

TRANEXAMIC ACID INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • None known

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

This information does not contain all possible interactions. Therefore, before using tranexamic acid, tell your doctor or pharmacist of all the products you use.

TRANEXAMIC ACID OVERDOSE

Symptoms of an overdose include feeling sick, being sick or feeling dizzy or light-headed on standing. If you accidentally take too much tranexamic acid, immediately tell your doctor or go to the nearest hospital casualty department. Remember to take any remaining tablets with you so that the doctor knows what you have taken.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of tranexamic acid or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose of tranexamic acid do not take that dose to catch up but take the next dose when it is due. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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