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Terms Of Use

VALSARTAN

Brand Name(s) : Diovan
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

VALSARTAN WARNINGS

Valsartan should be used with caution in: liver disease, severe kidney disease or are on dialysis, people who recently had a kidney transplant, patients who lost a lot of fluid by being sick or having diarrhoea, unilateral renal artery stenosis (narrowing of the blood vessels to one kidney), severe heart disease (other than heart failure or heart attack), disease of the heart valves or heart muscle, patients with primary hyperaldosteronism (disease of the adrenal glands), people taking medicines which increase potassium levels in the blood (e.g. potassium supplements, potassium sparing water tablets, heparin, salt substitutes containing potassium).

It should not be used in:

  • People allergic to valsartan or to any other ingredients in the medicine, women who are more than 3 months pregnant (it is also better to avoid valsartan in early pregnancy), severe liver disease, blockage of the bile duct.

Also see list of precautions and interactions

STORAGE

Store below 30ºC.

VALSARTAN USES

What is it used for?

  • Valsartan is used to reduce high blood pressure.
  • It is an angiotensin-II receptor antagonist, sometimes known as an antihypertensive.
  • It is used to treat high blood pressure (hypertension). Angiotensin II is produced in your body and causes your blood vessels to narrow, increasing your blood pressure. Valsartan blocks the effects of angiotensin II, so that your blood vessels relax and your blood pressure is lowered.
  • In general this drug is used to treat high blood pressure (hypertension). Valsartan can be used to treat heart failure when angiotensin converting enzymes (ACE) inhibitors cannot be used or in combination with ACE inhibitors when beta blockers cannot be used. Valsartan can also be used to treat people who had a heart attack in the past 12 hours to 10 days.
  • Benefits of being on this drug can include a reduction in blood pressure which is associated with a reduction in the risk of stroke, heart attack, heart failure, blindness or kidney failure.

Listed below are the typical uses of valsartan.

  • High blood pressure (hypertension) in adults and in children aged 6 years old and over

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • After a heart attack to improve survival and prevent further damage to the heart in adult patients.
  • Treatment of heart failure in adults

HOW TO USE/TAKE

Take this medication by mouth usually once a day, with or without food. Swallow the tablets whole with a glass of water.

Use this medication regularly in order to get the most benefit from it.

Remember to use it at the same time each day - unless specifically told not to by your doctor.

It may take up to four weeks before the full benefit of this drug takes effect.

Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Valsartan should not affect your ability to drive or operate machinery. However, medicines to treat high blood pressure can cause dizziness or tiredness. If you experience these symptoms, do not drive or operate machinery. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

VALSARTAN SIDE EFFECTS

If any of these persist or you consider them severe then inform your doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

  • Rash, itchiness and fever, swollen throat, face, eyelids or lips or inflamed blood vessels which may be a sign of an allergic reaction.
  • You feel sick or notice that you are passing less water (urine). This may be a sign of kidney problems
  • Yellowing of the skin or whites of the eyes or itchy skin which may be signs of changes in liver function.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

VALSARTAN PRECAUTIONS

Before taking valsartan, tell your doctor or pharmacist if you are allergic to it; or to other angiotensin-II receptor antagonists; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of: an allergy to valsartan or to any other ingredients in the medicine, you are pregnant or breastfeeding, or are trying to become pregnant, severe liver disease, blockage of the bile duct.

Before using this medication tell your doctor or pharmacist your medical history, especially any of the following liver disease, severe kidney disease, recent kidney transplant, you are being sick or have diarrhoea, unilateral renal artery stenosis (narrowing of the blood vessels to one kidney), severe heart disease (other than heart failure or heart attack), disease of the heart valves or heart muscle, primary hyperaldosteronism (disease of the adrenal glands).

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Patients should avoid alcohol while taking valsartan.

The elderly: valsartan can be used in the elderly.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Valsartan is not safe to take if you are, or are planning to become, pregnant.

Valsartan is not recommended in early pregnancy and must not be used in women who are more than 3 months pregnant.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Valsartan is not safe to take if you are breastfeeding

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

VALSARTAN INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • Potassium supplements
  • Salt substitutes containing potassium
  • Water tablets such as spironolactone, triamterene or amiloride
  • Lithium
  • Ciclosporin

If you are currently using any such medicine, tell your doctor or pharmacist before starting valsartan.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • ACE inhibitors such as captopril
  • Adrenergic neurone blockers
  • Alcohol
  • Aldesleukin
  • Alpha-blockers
  • Alprostadil
  • Anaesthetics
  • Medicines for mental illness (antipsychotics)
  • Medicines for anxiety
  • Medicines to help you sleep
  • Baclofen
  • Beta-blockers
  • Calcium channel blockers
  • Ciclosporin
  • Clonidine
  • Corticosteroids
  • Diazoxide
  • Drospirenone
  • Cimetidine
  • Glibenclamide
  • Heparin
  • Hydralazine
  • High doses of aspirin
  • Painkillers such as non-steroidal anti-inflammatory drugs (NSAIDs) or COX-2 inhibitors
  • Levodopa
  • Monoamine-oxidase inhibitors (MAOIs)
  • Methyldopa
  • Minoxidil
  • Moxisylyte
  • Moxonidine
  • Nitrates
  • Oestrogens
  • Sodium nitroprusside
  • Tacrolimus
  • Tizanidine

This information does not contain all possible interactions. Therefore, before using valsartan, tell your doctor or pharmacist of all the products you use.

VALSARTAN OVERDOSE

Taking too much valsartan may cause the following: low blood pressure (hypotension), loss of consciousness, collapse of the blood circulatory system and/or shock.

People who have taken too much valsartan should tell their doctor or nearest casualty department immediately. Take your medicine with you.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of valsartan or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you forget to take a dose take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and take the next dose at the usual time. Do not take a double dose to make up for a missed dose

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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