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Brand Name(s) : Benadryl, Benadryl Plus
Side Effects


Acrivastine should not be used in: patients who are allergic to Acrivastine or any of the ingredients, or to the antihistamine triprolidine; patients with kidney disease; children under 12 years old.

Also see list of precautions and interactions.


Do not store above 30°C. Store in the original package.


What is it used for?

  • Acrivastine is used to treat the symptoms of allergies, such as hayfever, hives and rashes (urticaria) and pet or dust allergies.
  • It is an antihistamine.
  • It is used to relieve the symptoms of allergies, such as sneezing, runny nose and watery eyes, in adults and children aged 12 to 65 years.
  • In general this drug is used to relieve the symptoms of hay fever and other allergic conditions such as pet or dust allergies. It can also be used to treat the symptoms of hives (urticaria) where the skin looks blotchy with white raised wheals (bumps) surrounded by redness.
  • Benefits of being on this drug can include relief from the symptoms that are caused by allergies.

Listed below are the typical uses of Acrivastine.

  • Relieve symptoms of hay fever (seasonal allergic rhinitis) such as runny or itchy nose, sneezing, itchy throat, and watery, itchy, or red eyes
  • Relieve symptoms of hives (chronic idiopathic urticaria) such as itching, swelling and rashes

On occasion your doctor may prescribe this medicine to treat a condition not on the above list.


How often do I take it?

  • Take this medication by mouth usually 3 times a day.
  • Use this medication when required (when you are suffering from the symptoms associated with an allergy: runny or itchy nose, sneezing, itchy throat, and watery, itchy, or red eyes) in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told not to by your doctor.
  • It may take up to 15 minutes before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Most people do not get drowsy when taking Acrivastine. However some people may be affected, if you are affected do not drive or operate machinery. Do not drink grapefruit juice while taking this medication. Consult your doctor or pharmacist for more details.

When can I stop?

  • Stop taking the medication when you feel better. If symptoms persist or worsen, talk to your doctor.


  • Drowsiness

If any of these persist or you consider them severe then inform your doctor or pharmacist.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website


Before taking Acrivastine, tell your doctor or pharmacist if you are allergic to it; or to other antihistamines; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of: kidney disease.

Before using this medication tell your doctor or pharmacist your medical history.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Limit the amount of alcohol you drink whilst taking this medication.

The elderly: acrivastine should be used with caution in the elderly because they may be more sensitive to its side effects, especially drowsiness.

Pregnancy and breastfeeding - please ensure you read the detailed information below


The safety of Acrivastine has not been established during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


It is not known whether Acrivastine passes into breast-milk. The manufacturer therefore states that it should not be taken if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Sedatives or tranquillisers (used to treat anxiety or sleep disorders).
  • Ketoconazole (an antifungal used to treat fungal infections).
  • Erythromycin (an antibiotic used to treat bacterial infections).

This information does not contain all possible interactions. Therefore, before using Acrivastine, tell your doctor or pharmacist of all the products you use.


The effects of overdose with Acrivastine are not known.

People who have taken too much Acrivastine should tell a doctor or go to a hospital casualty department straight away.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of Acrivastine or intentional overdose is suspected, contact your local hospital, GP or if in England call 111 or NHS Direct. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.


If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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