Boots WebMD Partners in Health
Return To Boots

Medicines & treatments centre

Terms Of Use

CALCITRIOL

Brand Name(s) : Rocaltrol, Silkis
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

CALCITRIOL WARNINGS

Calcitriol capsuless should be used with caution in:

  • People who previously have been taking a long-acting vitamin D preparation, such as ergocalciferol and colecalciferol
  • People who have a sudden increase in calcium in their diet, such as increasing the amounts of diary products eaten
  • People who are unable to move around a lot, such as those who have undergone surgery
  • Women who are pregnant.
  • Breastfeeding

Calcitriol capsules should not be used in case of:

  • An allergy (hypersensitivity) to calcitriol, vitamin D derivatives or any ingredient
  • Evidence of vitamin D poisoning (toxicity)
  • High levels of calcium in the blood (hypercalcaemia)
  • Extra calcium deposits in the body (metastatic calcification)
  • Rare hereditary problems in digesting sugars

Calcitriol ointment should be used with caution in:

  • Children
  • Patients taking calcium supplements, vitamin D or its derivatives, food containing vitamin D or other medicines that can increase the amount of calcium in the blood
  • Women who are pregnant
  • Treatment of the face.

Calcitriol ointment should not be used in case of:

  • An allergy (hypersensitivity) to calcitriol, vitamin D derivatives or any ingredient
  • Liver or kidney problems
  • High levels of calcium in the blood (hypercalcaemia)
  • Extra calcium deposits in the body (metastatic calcification)
  • Application under a wound dressing as it may lead to increased absorption of the ointment into they body, which could raise calcium levels.

Also see list of precautions and interactions.

STORAGE

Store calcitriol tablets below 25°C in the original package to protect from light and moisture.

There are no special storage conditions for calcitriol ointment.

CALCITRIOL USES

What is it used for?

  • Calcitriol tablets are used to treat bone disease in people with kidney problems (renal osteodystrophy) and weakening of the bones in women after the menopause (post-menopausal osteoporosis). Calcitriol ointment is used to treat a skin disorder called plaque psoriasis (psoriasis vulgaris).
  • It is a type of vitamin D analogue, sometimes known as a derivative of vitamin D.
  • It is used to slow down the growth of skin cells, which overgrow in the skin condition psoriasis and cause the skin to become scaly, thick and red. When taken as tablets, calcitriol makes your body absorb more calcium from your diet, which helps to form healthy bones and reduce bone damage.
  • In general this drug is used as a skin ointment for psoriasis and in tablet form to treat bone diseases.

Listed below are the typical uses of calcitriol:

  • Mild to moderately severe plaque psoriasis (psoriasis vulgaris) with up to 35% of the body surface affected
  • To treat established weakening of the bones in women after the menopause (post-menopausal osteoporosis)
  • To treat bone disease in people with kidney problems (renal osteodystrophy)

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below.

  • None known

HOW TO USE/TAKE

Always take calcitriol exactly as your doctor has told you.

Use this medication for the duration of the prescription in order to get the most benefit from it.

Remember to use it at the same time each day - unless specifically told otherwise by your doctor.

Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Calcitriol is not known to affect your ability to drive or operate machinery. Consult your doctor or pharmacist for more details.

When can I stop?

  • Always complete the full course as prescribed by your doctor.

CALCITRIOL SIDE EFFECTS

Calcitriol tablets:

  • High levels of calcium in the blood (hypercalcaemia)
  • High levels of calcium in the urine (hypercalciuria)
  • Changes in how well your liver is working (measured by blood tests)
  • Allergic (hypersensitivity) reactions

Calcitriol ointment:

  • Skin discomfort, itching and redness
  • Dry skin
  • Worsening of psoriasis.

If any of these persist or you consider them severe then stop taking calcitriol and inform doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

  • Severe skin irritation
  • Fever
  • Thirst
  • Stomach pain
  • Passing a lot of urine
  • Heartbeat problems (arrhythmias)
  • Hallucinations
  • Confusion.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

CALCITRIOL PRECAUTIONS

Before taking calcitriol, tell your doctor or pharmacist if you are allergic to it; or to other vitamin D derivatives; or if you have any other allergies.

Calcitriol capsules should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of:

  • An allergy (hypersensitivity) to calcitriol, vitamin D derivatives or any ingredient
  • Evidence of vitamin poisoning (toxicity)
  • A high level of calcium in the blood (hypercalcaemia)
  • A rare hereditary problem in digesting sugars

Before using calcitriol capsules, tell your doctor or pharmacist your medical history, especially any of the following:

  • If you have previously taken a long-acting vitamin D preparation, such as ergocalciferol and colecalciferol
  • A sudden increase in calcium intake in the diet, such as increasing the amounts of diary products eaten
  • If unable to move around a lot, such as after surgery
  • Dehydration
  • Kidney failure
  • Pregnancy.

Calcitriol ointment should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of:

  • An allergy (hypersensitivity) to calcitriol, vitamin D derivatives or any ingredient
  • Liver or kidney problems
  • A high level of calcium in the blood (hypercalcaemia)
  • Taking calcium supplements
  • Applying the medicine under a wound dressing.

Before using calcitriol ointment tell your doctor or pharmacist your medical history, especially any of the following:

  • Calcium supplements, vitamin D or its derivatives, food containing vitamin D or other medicines that can increase the amount of calcium in the blood
  • Pregnancy.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol is not known to affect this drug.

Children: calcitriol ointment should be used with caution in children as they may be more sensitive to its side effects.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

The safety of calcitriol has not been established during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

It should be assumed that calcitriol passes into breast milk. The manufacturer therefore states that it should not be used during breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

CALCITRIOL INTERACTIONS

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • None known.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Thiazide diuretics (water tablets), such as indapamide and metolazone, which may increase calcium levels in your blood (hypercalcaemia)
  • A drug used for heart problems called digitalis
  • Drugs used to prevent seizures called phenytoin and phenobarbital
  • Calcium supplements
  • High doses of vitamin D
  • Exfoliating, peeling or astringent products (ointment only)
  • Drugs that contain magnesium, such as antacids for indigestion
  • Corticosteroids that are used to treat a range of conditions, including skin diseases and joint pain or inflammation
  • A drug called colestyramine that is used to lower levels of fats in your blood, to prevent heart disease, to stop diarrhoea and to treat severe skin itching
  • Eating foods that contains extra vitamins or high levels of calcium
  • Antacids for indigestion.

This information does not contain all possible interactions. Therefore, before using calcitriol, tell your doctor or pharmacist of all the products you use.

CALCITRIOL OVERDOSE

If you use more calcitriol ointment than you should, you may develop redness, peeling, skin discomfort, feel sick, be sick, lose your appetite, feel depressed or not be able to pass stools regularly (constipation). If this occurs, contact your doctor.

If you take more calcitriol capsules than you should, contact your doctor or go to a hospital casualty department immediately. The signs of overdose include loss of appetite, feeling sick, being sick, headache, and feeling tired, drowsy or weak.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of calcitriol or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose of your calcitriol, take or apply it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Find a medication

Search by medication name for information on over-the-counter or prescription medications including side effects and interactions.
indicates detailed medicines information

Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

Search for a medicine or treatment

Search by medicine name or treatment for information including side effects and interactions.

Ex. Simvastatin, Ibuprofen, Amitriptyline Hydrochlorine

Popular Slideshows & Tools on Boots WebMD

woman looking at pregnancy test
Early pregnancy symptoms
donut on plate
The truth about sugar addiction
fish n chips
Diarrhoea & more
man coughing
10 common allergy triggers
couple watching sunset
How much do you know?
hand extinguishing cigarette
13 best tips to stop smoking
woman washing face
Living and dealing with eczema
boy looking at broccoli
Quick tips for feeding picky eaters
bag of crisps
Food cravings that wreck your diet
dogs face
Workout with Fido
polka dot dress on hangar
Lose weight without dieting