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Brand Name(s) : Nicef
Side Effects


Cefradine should be used with caution by: patients who are allergic (hypersensitivity) to penicillins or other drugs; patients who have other allergies, such as an allergy to any of the ingredients of the formulation (capsule or powder); patients with kidney damage.

It should not be used by patients who are allergic (hypersensitivity) to cefradine or other cephalosporins.

Also see list of precautions and interactions.


Store capsules below 25°C.


What is it used for?

  • Cefradine is used to treat a number of bacterial infections.
  • It is a member of a class of drugs called broad spectrum antibiotics, and specifically it is a cephalosporin-type antibiotic.
  • It is used to stop the growth of bacteria.
  • In general this drug is used to treat infections caused by bacteria.
  • Benefits of being on this drug can include the control or prevention of bacterial infections that may otherwise be harmful.

Listed below are the typical uses of cefradine:

On occasion your doctor may prescribe this medicine to treat a condition not on the above list. Such conditions are listed below: None known.


How often do I take it?

  • This medication is available as capsules.
  • The capsule should be taken orally, usually one to two capsules taken two to four times a day. The capsules should be swallowed whole with a glass of water. It does not matter if you take this medication with or without food.
  • Use this medication for duration of prescription in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take up to some hours before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Cefradine can sometimes cause dizziness, therefore your doctor may advise you not to drive or operate hazardous machinery. Consult your doctor or pharmacist for more details.

When can I stop?

  • Always complete the full course as prescribed by your doctor.


If any of these persist or you consider them severe then inform doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

  • abdominal or stomach pain/cramping; persistent nausea/vomiting; yellowing eyes or skin; dark urine; new signs of infection (e.g. persistent sore throat or fever); easy bruising/bleeding; change in the amount of urine; persistent diarrhoea; blood/mucus in your stool.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.


Before taking cefradine, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporin-type antibiotics, or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of: allergy to cefradine or to penicillins or other cephalosporins.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: kidney disease.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • There is no known interaction between cefradine and moderate amounts of alcohol, however your doctor may advise you not to drink whilst on this medication.

The elderly: cefradine should be used with caution in the elderly who may have impaired kidney or liver function.

Pregnancy and breastfeeding - please ensure you read the detailed information below


Cefradine is suitable to take during pregnancy, although caution should be exercised. Ask your doctor or pharmacist for advice before taking medication.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Cefradine is suitable to take if you are breastfeeding. However, caution should be taken when cefradine is administered to breastfeeding women as it is excreted in breast milk. Ask your doctor or pharmacist for advice before taking medication.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur: None known.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Loop diuretics (a class of diuretic agents that act by inhibiting re-absorption of sodium and chloride)
  • Blood-thinning medicines, such as warfarin
  • Probenecid (used mainly in the treatment of gout)
  • Water tablets e.g. furosemide

If you use chemical tests to check for sugar in your urine (diabetes), caution must be taken with the results as cefradine may cause a false positive reaction, however this does not occur with dipstick type tests.

This information does not contain all possible interactions. Therefore, before using cefradine, tell your doctor or pharmacist of all the products you use.


Symptoms of an overdose include: None known

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of cefradine or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.


If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited or TicTac Communications Ltd. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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