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Terms Of Use


Brand Name(s) : Canesten
Side Effects


Clotrimazole should not be used in:

  • People allergic to clotrimazole or any of the other ingredients in the medicine

Also see list of precautions and interactions


Do not store above 25°C.


What is it used for?

  • Clotrimazole is used to treat fungal infections.
  • It is an imidazole, sometimes known as an antifungal agent.
  • It is used to treat a variety of fungal infections.
  • In general this drug is used to treat fungal infections of the vagina as a vaginal cream or pessary. It is also used to treat fungal infections of the skin as a cream, spray, powder or solution.
  • Benefits of being on this drug can include effectively stopping the growth of the fungal infection and relief of the symptoms of the infection.

Listed below are the typical uses of clotrimazole:

On occasion your doctor may prescribe this medicine to treat a condition not on the above list.


Cream, spray, powder and solution

  • Clotrimazole is available as a cream, spray, powder or solution for fungal skin infections including ringworm, athlete’s foot, fungal nappy rash, sweat rash infections (armpit, groin, toes and skin folds) and thrush of the vulva or penis.
  • Apply the cream, spray, powder or solution to the affected area and the immediate surrounding area to prevent re-infection usually two or three times daily. Use this medication until symptoms of infection disappear in order to get the most benefit from it. The length of treatment required depends upon the type of infection, type of formulation and strength used. Generally, a minimum of 2 weeks is required for fungal skin infections treated with 1% cream, but it may take up to 4 weeks before the full benefit of this drug takes effect.
  • Vaginal cream and pessaryClotrimazole is available as a cream and as a pessary for insertion into the vagina. It is best when used at bedtime. Follow the instructions given in the patient information leaflet carefully to insert the pessary and/or apply the cream into the vagina, using the applicator provided. The pessaries are available in different strengths. The length of treatment required depends upon the strength of clotrimazole.

Remember to use it at the same time each day - unless specifically told otherwise by your doctor.

Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Use of clotrimazole in the vagina can make condoms or diaphragms less effective. If you use either of these methods of contraception, it is advisable to either use another method or to avoid sexual intercourse during treatment and for five days afterwards.
  • The use of the applicator to insert clotrimazole into the vagina is best avoided if you are pregnant.
  • Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue treatment as directed or until the symptoms of infection disappear. If the symptoms of a thrush infection do not improve within seven days of treatment then consult your doctor or pharmacist. If the medication is being used for the treatment of a sexual partner's penis, then treatment should be continued for up to two weeks.


If any of these persist or you consider them severe then inform your doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.


Before taking clotrimazole, tell your doctor or pharmacist if you are allergic to it; or to other imidazoles; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: Any of the following symptoms, if you are intending taking the medicine for vaginal thrush

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following if you are intending taking the medicine for vaginal thrush

  • - Pregnancy or possible pregnancy
  • - You are unsure that you have thrush, or it is the first time you have had the symptoms
  • - More than two infections of thrush in the last six months
  • - History of a sexually transmitted disease (you or partner)
  • - Aged under 16 or over 60 years

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Alcohol intake is not known to affect clotrimazole

The elderly: clotrimazole for vaginal use should be used with caution in the elderly (over 60 years).

Pregnancy and breastfeeding - please ensure you read the detailed information below


Clotrimazole is only suitable to take during pregnancy under the supervision of your doctor or midwife. Ask your doctor or pharmacist if you have any doubts or questions about this.

During pregnancy extra care should be taken if using clotrimazole with the vaginal applicator to prevent the possibility of mechanical trauma.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Clotrimazole is only suitable to take if you are breastfeeding under the supervision of your doctor.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Before using this medicine, tell your prescriber of all the medicines you are taking including prescription medicines and medicines you have bought over the counter without a prescription. Tell your prescriber if you are taking vitamins or complementary remedies such as herbal products, as these can also interact with medicines.

If you are taking more than one medicine, these may interact with each other. Your prescriber may decide to use medicines which interact with each other if the benefit outweighs the risks. In these cases, the dose of your medicines may need to be adjusted or you may be monitored more closely.

The following medicines may interact with clotrimazole:

This information does not contain all possible interactions. Therefore, tell your prescriber of all the products you are using before taking this medicine.

If you have a question or want to discuss anything about your medicine, speak to your local pharmacist.


This medicine is intended for topical use only. In the event of accidental oral ingestion, contact your doctor or local hospital. Routine measures such as gastric lavage should be performed only if serious symptoms of overdose become apparent (e.g. dizziness, nausea or vomiting). It should be carried out only if the airway can be protected adequately and in hospital.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of clotrimazole or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.


If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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