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Brand Name(s) : Froop, Frusid, Rusyde, Frusol, Minijet, Lasix, Frumul in combination with amiloride (co-amilofruse), Frumil LS in combination with amiloride (co-amilofruse), Aridil in combination with amiloride (co-amilofruse), Frusene in combination with triamterene, Lasilactone in combination with spironolactone
Side Effects


Furosemide should be used with caution in: the elderly, women who are pregnant, likely to become pregnant or who are breastfeeding, those with diabetes, gout or an enlarged prostate gland (e.g. have difficulty passing water), patients with low blood pressure (hypotension), those with severe blood and/or fluid loss (hypovolaemia), who are dehydrated or those who have mild or moderate liver or kidney problems.

It should not be used in: people who are allergic to furosemide or any other ingredient in the medicine, people with an allergy to any other diuretics or sulphonamide drugs, have severely low blood potassium levels (hypokalaemia) or severely low blood sodium levels (hyponatraemia), kidney failure, are not producing any urine (water), or certain states (comatose or precomatose states) in association with livercirrhosis (irreversible scarring of the liver).

Also see list of precautions and interactions.


Store below 25°C


Furosemide is used to treat a number of problems.

It is a member of a class of drugs called diuretics (specifically, the sub-group called loop diuretics) that remove water from the body by increasing the amount of urine the kidneys produce, and are sometimes called water tablets.

In general, this drug is used to treat fluid accumulation (oedema) owing to heart failure (fluid accumulates in the body as the heart is not pumping blood around the body as well as normal). lt can also be used to treat other conditions causing fluid to build up in the body such as certain liver and kidney disorders, and is also sometimes used to treat high blood pressure (hypertension).

Benefits of being on this drug include treatment of fluid accumulation and the relief of high blood pressure.

Listed below are the typical uses of furosemide.

  • Treatment of fluid accumulated in the body (oedema)
  • Control of high blood pressure (hypertension) that is resistant to treatment with an antihypertensive drug alone.

On occasion your doctor may prescribe this medicine to treat a condition not on the above list.


How often do I take it?

  • This medication is available to take orally as a tablet or as an oral solution, either of which should be taken orally, usually as a single dose in the morning. Tablets should be taken with a glass of water. Furosemide may also be given as an injection or an infusion.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take several hours before you notice any benefits of this drug.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy and use of certain interacting medicines.

Do I need to avoid anything?

  • If you feel less alert after taking furosemide do not drive or operate machinery. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.


Most common:

  • Altered balance of fluid or chemicals (e.g. sodium, potassium) in the body (symptoms such as dry mouth, tiredness, muscle pain, feeling sick, cramps, or fast heart rate)
  • Stomach irritation
  • Nausea (feeling sick)
  • Low blood pressure (hypotension)
  • Rash
  • Hyperuricaemia (high level of uric acid in the blood) and gout
  • Hyperglycaemia (high levels of glucose in the blood).


  • Tingling, numbness or 'pins and needle' sensations (paraesthesia)
  • Blood disorders (such as thrombocytopenia, leucopaenia, agranulosis, or anaemia), that can lead to symptoms such as tiredness, unusual bleeding or bruising, blood being slow to clot, or ulcers in the mouth or skin
  • Deafness
  • Ringing in the ears (tinnitus)
  • Rashes
  • Pancreatitis (symptoms of severe pain in the belly, back, feeling sick, vomiting and fever)
  • Temporary high level of fats (e.g. cholesterol) in the blood.

If any of these persist or you consider them severe then inform your doctor.

Tell your doctor immediately if you develop any of the following symptoms: rash, fever, joint or muscle pain may indicate inflammation of the blood vessels (vasculitis), or symptoms of kidney inflammation (blood in urine or may have a fever, feel sleepy or notice swelling of the ankles).

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.


Before taking furosemide, tell your doctor or pharmacist if you are allergic to it; or to other diuretics; to sulfonamide drugs or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: have any disorder of body chemical such as severely low blood potassium levels (hypokalaemia) or severely low blood sodium levels (hyponatraemia), severe kidney failure, or have liver cirrhosis (irreversible scarring of the liver).

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: low blood pressure (hypotension), are dehydrated, are not producing any water (urine), have recently experienced severe loss of blood (hypovolaemia), any previous occurrence of gout (indicated by severe pain in the joints), problems with the prostate gland (including difficulty in passing water (urine), or if you have diabetes or have recently had diarrhoea or think you may be dehydrated.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Yes. It may be harmful to patients suffering from alcoholism, and it can interact with diuretics causing further lowering of blood pressure, so avoid alcohol.

Pregnancy and breastfeeding - please ensure you read the detailed information below


The safety of furosemide has not been established during pregnancy. Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Furosemide is not safe to take if you are breastfeeding.

Ask your doctor or pharmacist if you have any doubts or questions about this.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • Antibacterials (lymecycline)
  • Antipsychotics (pimozide)
  • Cardiac glycosides

If you are currently using any of these medications, tell your doctor or pharmacist before starting furosemide.

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • Drugs for lowering blood pressure (antihypertensives) such as ACE (angiotensin-converting enzyme) inhibitors and alpha blockers (e.g. prazosin)
  • Anti-arrhythmics (e.g. digoxin, disopyramide and flecainide)
  • Antibacterials (e.g. aminoglycosides and vancomycin)
  • Antidepressants/anti-mania drugs (lithium)
  • Anti-epileptics, used to control fits (phenytoin or carbamazepine)
  • Beta-blockers (e.g. sotalol)
  • Non-steroidal anti-inflammatory drugs (e.g. aspirin or ibuprofen)
  • Anti-diabetes medication (e.g. insulin).

This information does not contain all possible interactions. Therefore, before using furosemide, tell your doctor or pharmacist of all the products you use.


Symptoms of an overdose include: dehydration and low levels of electrolytes (such as sodium and potassium). Severe potassium loss may lead to serious changes in heart rhythm (arrhythmias).

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of furosemide or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.


If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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