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Terms Of Use


Brand Name(s) : Nozinan
Side Effects


Levomepromazine should be used with caution in:

If you receive a large initial dose, you will have to stay in bed

It should not be used in:

  • Allergy to levomepromazine or to any other ingredient in the medicine

Also see list of precautions and interactions


Tablets should be stored below 25ºC.


What is it used for?

  • Levomepromazine is used to treat schizophrenia and relieve severe pain.
  • It is a neuroleptic, sometimes known as an antipsychotic.
  • In general this drug is used for the relief of severe pain and as a sedative to relieve the anxiety and stress associated with severe pain
  • Benefits of being on this drug can include anti-sickness, anti-histamine and anti-adrenaline effects.

Listed below are the typical uses of levomepromazine.

  • relief of severe pain,
  • a sedative to relieve anxiety and distress associated with severe pain,
  • schizophrenia,
  • relief of pain and accompanying restlessness or distress in the terminally ill patient.


How often do I take it?

  • Your doctor will prescribe the appropriate dosage for your condition. The medicine will be given either by mouth, by injection into a muscle or a vein, or slowly via a needle under the skin.
  • When taken by mouth, tablets should be taken usually every 4 to 8 hours. The dose may be varied until the most suitable dose is found.
  • Use this medication as instructed by your doctor in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take up to three hours before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Do not drive or operate machinery whilst receiving levomepromazine as it may make you feel drowsy, confused, dizzy or lightheaded.
  • Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, until your doctor tells you to stop.


If any of these persist or you consider them severe then inform your doctor.

Tell your doctor immediately if you develop any of the following symptoms:

  • Dizziness, feeling faint or loss of alertness.
  • Skin irritation or rash especially after going out in the sun, which may result in burning.
  • Fever, ulceration of mouth or throat, or a sore throat.
  • Tremors or shaking, muscle stiffness.
  • Jaundice – yellowing of the skin and eyes.
  • High temperature, sweating, pale complexion, difficulty in passing urine.
  • Constipation, which may become severe and stop food moving through the bowel.
  • Heart palpitations (usually rapid or irregular heartbeats).
  • Unwanted and persistent erections.
  • Colickyabdominal pain with bloody diarrhoea.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.


Before taking levomepromazine, tell your doctor or pharmacist if you are allergic to it; or to other neuroleptics; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you are pregnant.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following:

  • Liver disease
  • heart problems
  • elderly
  • debilitated (frail)
  • slow heart rate
  • low levels of calcium, magnesium or potassium in the blood
  • starvation
  • alcohol abuse
  • allergies to phenothiazines or any of the ingredients
  • slow or irregular heartbeats or palpitations, or a family history of them
  • unable, or finding it difficult, to eat

If you receive a large initial dose, you will have to stay in bed.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Avoid alcohol whilst taking levomepromazine.

The elderly: levomepromazine should be used with caution in the elderly as it may cause dizziness, fainting and/or lightheadedness.

Pregnancy and breastfeeding - please ensure you read the detailed information below


Levomepromazine is not safe to take if you are, or are planning to become, pregnant.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Levomepromazine is not safe to take if you are breastfeeding.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

  • none known

Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:

  • desferrioxamine (for iron poisoning),
  • adrenaline (epinephrine),
  • medicines for the treatment of irregular heartbeats,
  • medicines for the treatment of depression and other mental health disorders.

This information does not contain all possible interactions. Therefore, before using levomepromazine, tell your doctor or pharmacist of all the products you use.


As the injection is given by the doctor or nurse it is unlikely that too much will be given. However, if you are worried talk to your doctor or nurse.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of levomepromazine or intentional overdose is suspected, IMMEDIATELY contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.


If you miss an injection, contact your doctor or nurse, as soon as you remember, to arrange for another appointment for your next injection.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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