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PYRIDOXINE (ABIDEC (WITH VITAMIN A, VITAMIN D, THIAMINE, RIBOFLAVIN, NICOTINAMIDE AND ASCORBIC ACID))

Brand Name(s) : Abidec (with vitamin A, vitamin D, thiamine, riboflavin, nicotinamide and ascorbic acid), Calcimax (with ascorbic acid, calciferol, calcium glycine HCl, calcium pantothenate, cyanobalamin, nicotinamide, riboflavin and thiamine), Concavit (with various vitamins and minerals; composition varies in drops, capsules and syrup), Ketovite (with various vitamins and minerals; composition varies in liquid and tablets), Orovite (with thiamine, riboflavin, nicotinamide and ascorbic acid), Orovite '7' (with vitamin A, vitamin D, thiamine, riboflavin, nicotinamide and ascorbic acid), Pabrinex (high potency vitamins B and C), Pharmaton (with, vitamin A, cholecalciferol, tocopherol, thiamine, riboflavin, cyanocobalamin, biotin, nicotinamide, ascorbic acid, folic acid, copper sulphate, sodium selenite, magnesium sulphate, iron sulphate, zinc sulphate, calcium phosphate and lecithin), Vigranon-B (with thiamine, riboflavin, nicotinamide and panthenol)
Warnings
Uses
Side Effects
Precautions
Interactions
Overdose

PYRIDOXINE WARNINGS

Thiamine should be used with caution in:

  • None known.

It should not be used in:

  • Allergy to pyridoxine or to any other ingredient in the product

Also see list of precautions and interactions.

STORAGE

Store away from direct sunlight below 25°C

PYRIDOXINE USES

What is it used for?

  • Pyridoxine is used to treat a number of problems.
  • It is vitamin B6, and is sometimes known as a vitamin supplement or a multivitamin when used in preparations containing other vitamins and minerals.
  • It is used to treat deficiencies (lack of) vitamin B6.
  • In general this drug is used to treat fatigue, drowsiness and feeling 'run down', particularly when a lack of dietary vitamins is suspected and when given as a vitamin supplement, and is sometimes given for the prevention of vitamin deficiencies and for the maintenance of normal health during the early years of childhood, often when used alongside other vitamins and minerals. It is also used as a liquid (with other B vitamins and vitamin C) for intravenous or intramuscular injection in certain situations to correct low levels of vitamins B and C which may have occurred (e.g. in alcoholism, after infections, after operations and in certain psychiatric states).
  • Benefits of being on this drug can include a feeling of increased 'energy levels' and treatment of symptoms of vitamin B deficiency.

Listed below are the typical uses of pyridoxine.

  • Treating and preventing vitamin B6 deficiencies
  • Treating idiopathic sideroblastic anaemia (where the red cells in the blooddo not form properly)
  • Preventing damage to the nerves causing 'pins and needles', which can occur after treatment with isoniazid, used to treat for tuberculosis.

On occasion your doctor may prescribe this medicine to treat a condition not on the above list.

HOW TO USE/TAKE

How often do I take it?

  • Take this medication by mouth, usually one- to three-times daily, with or without food. Tablets should be swallowed with a drink of water. It is also available as a liquid to take by mouth, and as a liquid for injection.
  • Use this medication regularly in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told otherwise by your doctor.
  • It may take some time before the full benefit of this drug takes effect.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • None known. Consult your doctor or pharmacist for more details.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.

PYRIDOXINE SIDE EFFECTS

  • Low blood pressure (hypotension) (intravenous or intramuscular injections)
  • Mild tingling, numbness or 'pins and needle' sensations (paraesthesia) from continued intravenous or intramuscular injections
  • Mild ache at injection site (intravenous or intramuscular injections).

If any of these persist or you consider them severe then inform doctor or pharmacist.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.

PYRIDOXINE PRECAUTIONS

Before taking pyridoxine, tell your doctor or pharmacist if you are allergic to it; or to other vitamins; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • None known.

Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following: if you are taking other vitamin supplements allowance should be made for vitamins obtained from these other sources to prevent hypervitaminosis.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • It is not known whether drinking alcohol affects this drug's action.

The elderly: pyridoxine can be used in the elderly.

Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY

Pyridoxine should only be taken during pregnancy if your doctor thinks you need it.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING

Pyridoxine should only be taken while breastfeeding if your doctor thinks you need it.

It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

PYRIDOXINE INTERACTIONS

Before using this medicine, tell your prescriber of all the medicines you are taking including prescription medicines and medicines you have bought over the counter without a prescription. Tell your prescriber if you are taking vitamins or complementary remedies such as herbal products, as these can also interact with medicines.

If you are taking more than one medicine, these may interact with each other. Your prescriber may decide to use medicines which interact with each other if the benefit outweighs the risks. In these cases, the dose of your medicines may need to be adjusted or you may be monitored more closely.

The following medicines may interact with pyridoxine:

  • Antiparkinsonian drugs such as levodopa.

This information does not contain all possible interactions. Therefore, tell your prescriber of all the products you are using before taking this medicine.

If you have a question or want to discuss anything about your medicine, speak to your local pharmacist.

PYRIDOXINE OVERDOSE

No side effects of overdose of this medicine are known.

If you think you, or someone you care for, might have accidentally taken more than the recommended dose of thiamine or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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