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Brand Name(s) : Cordilox, Securon IV, Securon SR, Half Securon SR, Tarka (with trandolapril), Univer, Verapress MR, Vertab SR 2
Side Effects


Verapamil hydrochloride should be used with caution in patients who:
are pregnant, planning to become pregnant or are breast feeding, are sensitive to any ingredients in the medication, have had a heart attack or heart failure, have a slow heart rate, have low blood pressure, have Wolff-Parkinson-White syndrome, a condition in which the heart rate is rapid, have liver disease, or are taking medicines such as beta blockers, carbamazepine, cimetidine, ciclosporin, digitalis, digoxin, lithium, phenobarbital, phenytoin, rifampicin, theophylline, and other drugs for high blood pressure.

It should not be used in:
Patients with low blood pressure (hypotension), heart problems such as slow heartbeat (bradycardia), a history of heart failure and Wolff-Parkinson-White syndrome, a condition in which the heart rate is rapid, and other related syndrome; or acute porphyria (an inherited condition that affects red blood cells leading to blisters, abdominal pain and other symptoms).

Also see list of precautions and interactions.


Store below 25°C in a dry place in the original packaging.


What is it used for?

  • Verapamil hydrochloride is used to treat problems related to the heart and circulation. It is a calcium channel blocker.
  • It works by relaxing and opening up the blood vessels, enabling blood to flow more freely around the body.
  • Benefits of being on this drug include reduced blood pressure, a more regular heart rhythm and decreased likelihood of heart attack in patients who have had a previous heart attack.

Listed below are the typical uses of verapamil hydrochloride:

  • To treat hypertension
  • To treat angina
  • To prevent heart attack (myocardial infarction) in patients who have previously had a heart attack
  • To control irregular heartbeats (arrhythmias).


How often do I take it?

  • Your doctor will tell you how often to take verapamil hydrochloride. Use this medication for the duration of prescription in order to get the most benefit from it.
  • Remember to use it at the same time each day - unless specifically told not to by your doctor.
  • Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

  • Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

  • Verapamil may affect your ability to drive a vehicle or operate machinery, particularly when starting treatment. If affected, do not drive or operate machinery. Do not drink grapefruit juice while you are taking verapamil.

When can I stop?

  • It is important to continue taking this medication even if you feel well, unless your doctor tells you to stop.



If any of these persist or you consider them severe then inform your doctor or pharmacist.

Tell your doctor immediately if you develop any of the following symptoms:

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine (which includes vaccines, herbals and over the counter medicines) that you are taking. It is run by the medicines safety watchdog called the Medicines and Healthcare products Regulatory agency (MHRA). Please report any suspected side effect on the Yellow Card Scheme website.


Before taking verapamil hydrochloride, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers; or if you have any other allergies.

Before using this medication tell your doctor or pharmacist your medical history, especially any of the following:

  • Had a heart attack or heart failure
  • A slow heart rate
  • Low blood pressure
  • Wolff-Parkinson-White syndrome, in which a rapid heart rate is sometimes associated with dizziness or faintness
  • Liver disease

Before having surgery, tell your doctor or dentist that you are taking this medication.

Does alcohol intake affect this drug?

  • Yes. Verapamil hydrochloride increases blood alcohol levels. You should avoid excessive amounts of alcohol whilst taking this drug.

The elderly: verapamil hydrochloride may be used in the elderly.

Pregnancy and breastfeeding - please ensure you read the detailed information below


You should not take verapamil hydrochloride during the first trimester of pregnancy unless your doctor decides it is essential for your welfare.

It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Verapamil hydrochloride passes into the breast milk in small amounts and is unlikely to be harmful. However, on rare occasions an allergic reaction to the medication has been reported. Your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation.

If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.


Before using this medicine, tell your prescriber of all the medicines you are taking including prescription medicines and medicines you have bought over the counter without a prescription. Tell your prescriber if you are taking vitamins or complementary remedies such as herbal products, as these can also interact with medicines.

If you are taking more than one medicine, these may interact with each other. Your prescriber may decide to use medicines which interact with each other if the benefit outweighs the risks. In these cases, the dose of your medicines may need to be adjusted or you may be monitored more closely.

The following medicines may interact with verapamil:

  • Beta-blockers
  • Medicines for epilepsy including phenytoin, phenobarbital and carbamazepine
  • Cimetidine
  • Ciclosporin
  • Digoxin or digitoxin
  • Lithium
  • Rifampicin
  • Theophylline
  • Medicines for depression
  • Any other medicines for high blood pressure
  • Any over-the-counter medicines including St John’s Wort

This information does not contain all possible interactions. Therefore, tell your prescriber of all the products you are using before taking this medicine.

If you have a question or want to discuss anything about your medicine, speak to your local pharmacist.


If you think you, or someone you care for, might have accidentally taken more than the recommended dose of verapamil hydrochloride or intentional overdose is suspected, contact your local hospital, GP or if in England call 111. In Scotland call NHS 24. In Wales, call NHS Direct Wales. In the case of medical emergencies, always dial 999.


If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

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Source: Selected from data included with permission and copyrighted by Boots UK Limited. This copyrighted material is sourced from a licensed data provider and is not for distribution, except as may be authorised by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse events, nor should it be construed to indicate that use of a particular medicine is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any medicine, changing any diet, or discontinuing any course of treatment.

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